Richard W Farndale
Overview
Explore the profile of Richard W Farndale including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
148
Citations
4746
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chen D, Du Y, Llewellyn J, Bonna A, Zuo B, Janmey P, et al.
J Biol Chem
. 2024 Nov;
300(12):107968.
PMID: 39510178
Type I collagen is the most abundant structural protein in the body and, with other fibrillar collagens, forms the fibrous network of the extracellular matrix. Another group of extracellular matrix...
2.
Singh A, Mommers-Elshof E, Vijver S, Jansen J, Gonder S, Lebbink R, et al.
Cancer Immunol Immunother
. 2024 Jan;
73(1):16.
PMID: 38236251
Collagen expression and structure in the tumour microenvironment are associated with tumour development and therapy response. Leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1) is a widely expressed inhibitory collagen receptor. LAIR-2 is a...
3.
Alexander S, Fabbro D, Kelly E, Mathie A, Peters J, Veale E, et al.
Br J Pharmacol
. 2023 Dec;
180 Suppl 2:S241-S288.
PMID: 38123155
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of...
4.
Induruwa I, Kempster C, Thomas P, McKinney H, Malcor J, Bonna A, et al.
TH Open
. 2023 Nov;
7(4):e294-e302.
PMID: 37964899
Atrial fibrillation (AF) increases the risk of ischemic stroke (IS). We hypothesized that the functional form of platelet receptor glycoprotein (GP) VI, GPVI-dimer, which binds to collagen and fibrin causing...
5.
Ishikawa Y, Bonna A, Gould D, Farndale R
Int J Mol Sci
. 2023 Oct;
24(20).
PMID: 37894834
Mutations in the gene encoding the endoplasmic reticulum resident collagen-related proline isomerase FK506 binding protein 22 kDa (FKBP22) result in kyphoscoliotic Ehlers-Danlos Syndrome (EDS), which is characterized by a broad...
6.
Jooss N, Smith C, Pike J, Farndale R, Henskens Y, Watson S, et al.
J Thromb Haemost
. 2023 May;
21(8):2260-2267.
PMID: 37150294
Background: Collagen-induced platelet activation is predominantly mediated by glycoprotein (GP) VI through formation of receptor clusters that coincide with the accumulation of signaling molecules and are hypothesized to drive strong...
7.
Jooss N, Henskens Y, Watson S, Farndale R, Gawaz M, Jandrot-Perrus M, et al.
Thromb Haemost
. 2023 Feb;
123(6):597-612.
PMID: 36807826
Background: In secondary cardiovascular disease prevention, treatments blocking platelet-derived secondary mediators pose a risk of bleeding. Pharmacological interference of the interaction of platelets with exposed vascular collagens is an attractive...
8.
Hunter E, Hamaia S, Kim P, Malcor J, Farndale R
Sci Rep
. 2022 Dec;
12(1):21601.
PMID: 36517525
Blood vessels in the body are lined with endothelial cells which have vital roles in numerous physiological and pathological processes. Collagens are major constituents of the extracellular matrix, and many...
9.
Moroi M, Induruwa I, Farndale R, Jung S
Res Pract Thromb Haemost
. 2022 May;
6(3):e12697.
PMID: 35494504
Background: In the fibrin-forming process, thrombin cleaves fibrinogen to fibrin, which form fibrils and then fibers, producing a gel-like clot. Thrombin also activates coagulation factor XIII (FXIII), which crosslinks fibrin...
10.
Jensen M, Bonna A, Frederiksen S, Hamaia S, Hojrup P, Farndale R, et al.
Biochim Biophys Acta Proteins Proteom
. 2022 Mar;
1870(5):140771.
PMID: 35306228
Dermatopontin (DPT), a small extracellular matrix protein that stimulates collagen fibrillogenesis, contains sulfotyrosine residues but neither its level of sulfation nor its binding sites on fibrillar collagens are known. Here,...