Richard Siller
Overview
Explore the profile of Richard Siller including associated specialties, affiliations and a list of published articles.
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17
Citations
275
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0
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Recent Articles
1.
Westerberg N, Atneosen-Asegg M, Melheim M, Chollet M, Harrison S, Siller R, et al.
Pediatr Res
. 2024 Jul;
97(1):195-201.
PMID: 38951656
Objectives: Hepatic ischemia and hypoxia are accompanied by reduced bile flow, biliary sludge and cholestasis. Hepatobiliary transport systems, nuclear receptors and aquaporins were studied after hypoxia and reoxygenation in human...
2.
Hong Y, Zhang Z, Yangzom T, Chen A, Lundberg B, Fang E, et al.
Int J Biol Sci
. 2024 Feb;
20(4):1194-1217.
PMID: 38385069
Alpers' syndrome is an early-onset neurodegenerative disorder usually caused by biallelic pathogenic variants in the gene encoding the catalytic subunit of polymerase-gamma (POLG), which is essential for mitochondrial DNA (mtDNA)...
3.
Lin X, Wang W, Yang M, Damseh N, de Sousa M, Jacob F, et al.
Genome Biol
. 2023 Sep;
24(1):216.
PMID: 37773136
Background: Oxidation Resistance 1 (OXR1) gene is a highly conserved gene of the TLDc domain-containing family. OXR1 is involved in fundamental biological and cellular processes, including DNA damage response, antioxidant...
4.
Harrison S, Siller R, Tanaka Y, Chollet M, de la Morena-Barrio M, Xiang Y, et al.
Exp Mol Med
. 2023 Aug;
55(9):2005-2024.
PMID: 37653039
The lack of physiological parity between 2D cell culture and in vivo culture has led to the development of more organotypic models, such as organoids. Organoid models have been developed...
5.
Sharma K, Asp N, Harrison S, Siller R, Baumgarten S, Gupta S, et al.
Autophagy
. 2021 Dec;
18(8):1915-1931.
PMID: 34923909
Early events during development leading to exit from a pluripotent state and commitment toward a specific germ layer still need in-depth understanding. Autophagy has been shown to play a crucial...
6.
Mostafavi S, Balafkan N, Pettersen I, Nido G, Siller R, Tzoulis C, et al.
Front Cell Dev Biol
. 2021 Nov;
9:744777.
PMID: 34722525
Given the considerable interest in using stem cells for modeling and treating disease, it is essential to understand what regulates self-renewal and differentiation. Remodeling of mitochondria and metabolism, with the...
7.
Balafkan N, Mostafavi S, Schubert M, Siller R, Liang K, Sullivan G, et al.
Sci Rep
. 2020 Oct;
10(1):18498.
PMID: 33116175
The capacity of pluripotent stem cells both for self-renewal and to differentiate into any cell type have made them a powerful tool for studying human disease. Protocols for efficient differentiation...
8.
Liang K, Kristiansen C, Mostafavi S, Vatne G, Zantingh G, Kianian A, et al.
EMBO Mol Med
. 2020 Aug;
12(10):e12146.
PMID: 32840960
Mutations in POLG disrupt mtDNA replication and cause devastating diseases often with neurological phenotypes. Defining disease mechanisms has been hampered by limited access to human tissues, particularly neurons. Using patient...
9.
Magaletta M, Siller R, Maehr R
Curr Top Dev Biol
. 2020 Mar;
138:175-208.
PMID: 32220297
The pharyngeal apparatus, a transient embryological structure, includes diverse cells from all three germ layers that ultimately contribute to a variety of adult tissues. In particular, pharyngeal endoderm produces cells...
10.
Pisal R, Suchanek J, Siller R, Soukup T, Hrebikova H, Bezrouk A, et al.
Sci Rep
. 2018 Apr;
8(1):6168.
PMID: 29670257
The aim of this study was to extensively characterise natal dental pulp stem cells (nDPSC) and assess their efficiency to generate human induced pluripotent stem cells (hiPSC). A number of...