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Richard S Eisenstein

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Articles 31
Citations 1462
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21.
Wallander M, Leibold E, Eisenstein R
Biochim Biophys Acta . 2006 Jul; 1763(7):668-89. PMID: 16872694
Both deficiencies and excesses of iron represent major public health problems throughout the world. Understanding the cellular and organismal processes controlling iron homeostasis is critical for identifying iron-related diseases and...
22.
Pondarre C, Antiochos B, Campagna D, Clarke S, Greer E, Deck K, et al.
Hum Mol Genet . 2006 Feb; 15(6):953-64. PMID: 16467350
Proteins with iron-sulfur (Fe-S) clusters participate in multiple metabolic pathways throughout the cell. The mitochondrial ABC half-transporter Abcb7, which is mutated in X-linked sideroblastic anemia with ataxia in humans, is...
23.
Clarke S, Vasanthakumar A, Anderson S, Pondarre C, Koh C, Deck K, et al.
EMBO J . 2006 Jan; 25(3):544-53. PMID: 16424901
The generally accepted role of iron-regulatory protein 1 (IRP1) in orchestrating the fate of iron-regulated mRNAs depends on the interconversion of its cytosolic aconitase and RNA-binding forms through assembly/disassembly of...
24.
Elchuri S, Oberley T, Qi W, Eisenstein R, Roberts L, Van Remmen H, et al.
Oncogene . 2004 Nov; 24(3):367-80. PMID: 15531919
Mice deficient in CuZn superoxide dismutase (CuZnSOD) showed no overt abnormalities during development and early adulthood, but had a reduced lifespan and increased incidence of neoplastic changes in the liver....
25.
Pitula J, Deck K, Clarke S, Anderson S, Vasanthakumar A, Eisenstein R
Proc Natl Acad Sci U S A . 2004 Jul; 101(30):10907-12. PMID: 15263083
Iron-regulatory protein 1 (IRP1) is a dual-function protein with mutually exclusive roles as a posttranscriptional regulator of animal-cell iron metabolism or as the cytosolic isoform of the iron-sulfur enzyme aconitase...
26.
Bradley J, Leibold E, Harris Z, Wobken J, Clarke S, Zumbrennen K, et al.
Am J Physiol Regul Integr Comp Physiol . 2004 Jun; 287(4):R894-901. PMID: 15178542
Placental iron transport during the last trimester of pregnancy determines the iron endowment of the neonate. Iron transport is a function of the major iron transport proteins: transferrin receptor-1 (TfR-1)...
27.
Eisenstein R, Ross K
J Nutr . 2003 May; 133(5 Suppl 1):1510S-6S. PMID: 12730455
Iron regulatory proteins (IRP) modulate the use of mRNA-encoding proteins that are involved in the transport, storage and use of iron. Several new potential mRNA targets for IRP were recently...
28.
Ross K, Eisenstein R
J Nutr . 2002 Apr; 132(4):643-51. PMID: 11925455
Mitochondrial aconitase (m-acon) is the tricarboxylic acid (TCA) cycle enzyme that converts citrate to isocitrate. m-Acon mRNA is a potential target for regulation by iron regulatory proteins (IRPs), suggesting a...
29.
Gorman N, Ross K, Walton H, Bement W, Szakacs J, Gerhard G, et al.
Hepatology . 2002 Mar; 35(4):912-21. PMID: 11915039
In mice treated with 5-aminolevulinic acid (ALA) and polyhalogenated aromatic compounds, the levels of both hepatic cytochrome P450 (CYP)1A2 and iron-which can be quite different among inbred strains-are critical in...
30.
Roy C, Blemings K, Deck K, Davies P, Anderson E, Eisenstein R, et al.
J Cell Physiol . 2002 Jan; 190(2):218-26. PMID: 11807826
Iron regulatory proteins (IRPs), the cytosolic proteins involved in the maintenance of cellular iron homeostasis, bind to stem loop structures found in the mRNA of key proteins involved iron uptake,...