Aparna Vasanthakumar
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Explore the profile of Aparna Vasanthakumar including associated specialties, affiliations and a list of published articles.
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4840
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Recent Articles
1.
Croney R, Fristed E, Masterman D, Meyer M, Sachdev P, Vasanthakumar A, et al.
Alzheimers Dement
. 2024 Dec;
21(1):e14248.
PMID: 39711065
The Alzheimer's Disease Neuroimaging Initiative (ADNI) Private Partners Scientific Board (PPSB) Diversity, Equity, and Inclusion Working Group (DE&I WG) was established to work with the ADNI3 Diversity Task Force to...
2.
Nho K, Risacher S, Apostolova L, Bice P, Brosch J, Deardorff R, et al.
Nat Commun
. 2024 Sep;
15(1):8251.
PMID: 39304655
Determining the genetic architecture of Alzheimer's disease pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we perform a genome-wide association study of cortical tau quantified by positron...
3.
Greenberg E, Voorbach M, Smith A, Reuter D, Zhuang Y, Wang J, et al.
Heliyon
. 2024 Sep;
10(16):e36483.
PMID: 39253182
Alzheimer's disease (AD) is the most common global dementia and is universally fatal. Most late-stage AD disease-modifying therapies are intravenous and target amyloid beta (Aβ), with only modest effects on...
4.
Ideozu J, Liu M, Riley-Gillis B, Paladugu S, Rahimov F, Krishnan P, et al.
Genome Med
. 2024 Mar;
16(1):43.
PMID: 38515211
Background: Limited understanding of the diversity of variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene across ancestries hampers efforts to advance molecular diagnosis of cystic fibrosis (CF). The...
5.
Albala B, Appelmans E, Burress R, De Santi S, Devins T, Klein G, et al.
Alzheimers Dement
. 2023 Sep;
20(1):695-708.
PMID: 37774088
The Alzheimer's Disease Neuroimaging Initiative (ADNI) Private Partners Scientific Board (PPSB) encompasses members from industry, biotechnology, diagnostic, and non-profit organizations that have until recently been managed by the Foundation for...
6.
Cunningham M, Pins D, Dezso Z, Torrent M, Vasanthakumar A, Pandey A
J Cheminform
. 2023 Jul;
15(1):64.
PMID: 37468968
The identification of human proteins that are amenable to pharmacologic modulation without significant off-target effects remains an important unsolved challenge. Computational methods have been devised to identify features which distinguish...
7.
Nho K, Risacher S, Apostolova L, Bice P, Brosch J, Deardorff R, et al.
medRxiv
. 2023 Mar;
PMID: 36993271
Determining the genetic architecture of Alzheimer's disease (AD) pathologies can enhance mechanistic understanding and inform precision medicine strategies. Here, we performed a genome-wide association study of cortical tau quantified by...
8.
de Vasconcellos J, Abedalthagafi M, Calo S, Dajani R, Dlamini Z, Hidalgo B, et al.
Front Genet
. 2022 Oct;
13:1038317.
PMID: 36263431
No abstract available.
9.
Kim B, Vasanthakumar A, Li Q, Nudelman K, Risacher S, Davis J, et al.
Alzheimers Dement (Amst)
. 2022 Oct;
14(1):e12354.
PMID: 36187194
Introduction: The acceleration of biological aging is a risk factor for Alzheimer's disease (AD). Here, we performed weighted gene co-expression network analysis (WGCNA) to identify modules and dysregulated genesinvolved in...
10.
Li Q, Vasanthakumar A, Davis J, Idler K, Nho K, Waring J, et al.
Clin Epigenetics
. 2021 Oct;
13(1):191.
PMID: 34654479
Background: Identifying biomarkers associated with Alzheimer's disease (AD) progression may enable patient enrichment and improve clinical trial designs. Epigenome-wide association studies have revealed correlations between DNA methylation at cytosine-phosphate-guanine (CpG)...