Richard J Dobson
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Explore the profile of Richard J Dobson including associated specialties, affiliations and a list of published articles.
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31
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1194
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Recent Articles
1.
Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS
Marriott H, Spargo T, Al Khleifat A, Andersen P, Basak N, Cooper-Knock J, et al.
Ann Clin Transl Neurol
. 2024 May;
11(7):1775-1786.
PMID: 38775181
Objective: Neurofilament heavy-chain gene (NEFH) variants are associated with multiple neurodegenerative diseases, however, their relationship with ALS has not been robustly explored. Still, NEFH is commonly included in genetic screening...
2.
Marriott H, Kabiljo R, Hunt G, Al Khleifat A, Jones A, Troakes C, et al.
Acta Neuropathol Commun
. 2023 Dec;
11(1):208.
PMID: 38129934
Amyotrophic lateral sclerosis (ALS) displays considerable clinical and genetic heterogeneity. Machine learning approaches have previously been utilised for patient stratification in ALS as they can disentangle complex disease landscapes. However,...
3.
Au Yeung J, Kraljevic Z, Luintel A, Balston A, Idowu E, Dobson R, et al.
Front Digit Health
. 2023 May;
5:1161098.
PMID: 37122812
As large language models (LLMs) expand and become more advanced, so do the natural language processing capabilities of conversational AI, or "chatbots". OpenAI's recent release, ChatGPT, uses a transformer-based model...
4.
Marriott H, Kabiljo R, Al Khleifat A, Dobson R, Al-Chalabi A, Iacoangeli A
Bioinformatics
. 2023 Apr;
39(4).
PMID: 37010501
Summary: The current widespread adoption of next-generation sequencing (NGS) in all branches of basic research and clinical genetics fields means that users with highly variable informatics skills, computing facilities and...
5.
Farajidavar N, OGallagher K, Bean D, Nabeebaccus A, Zakeri R, Bromage D, et al.
BMC Cardiovasc Disord
. 2022 Dec;
22(1):567.
PMID: 36567336
Background: Heart failure with preserved ejection fraction (HFpEF) is thought to be highly prevalent yet remains underdiagnosed. Evidence-based treatments are available that increase quality of life and decrease hospitalization. We...
6.
Iacoangeli A, Fogh I, Selvackadunco S, Topp S, Shatunov A, van Rheenen W, et al.
Brain Commun
. 2021 Oct;
3(4):fcab236.
PMID: 34708205
Evidence indicates that common variants found in genome-wide association studies increase risk of disease through gene regulation via expression Quantitative Trait Loci. Using multiple genome-wide methods, we examined if Single...
7.
Carr E, Federman A, Dzahini O, Dobson R, Bendayan R
Sci Rep
. 2021 Apr;
11(1):8783.
PMID: 33888728
Polypharmacy is commonly defined based on the number of medications taken concurrently using standard cut-offs, but several studies have highlighted the need for a multidimensional assessment. We developed a multidimensional...
8.
Outcomes of adults with repaired tetralogy of Fallot from the national Scottish Cohort - CORRIGENDUM
Dobson R, Ramparsad N, Walker N, McConnachie A, Danton M
Cardiol Young
. 2021 Mar;
31(4):686.
PMID: 33719994
No abstract available.
9.
Dobson R, Ramparsad N, Walker N, McConnachie A, Danton M
Cardiol Young
. 2021 Feb;
31(8):1306-1314.
PMID: 33622440
Background: The adult population of repaired tetralogy of Fallot is increasing and at risk of pre-mature death and arrhythmia. This study evaluates risk factors for adverse outcome and the effect...
10.
Bendayan R, Mascio A, Stewart R, Roberts A, Dobson R
Am J Geriatr Psychiatry
. 2020 Nov;
29(6):604-616.
PMID: 33250337
Objectives: We aimed to compare trajectories of cognitive performance in individuals diagnosed with dementia with and without severe mental illness (SMI). Design: Retrospective cohort study. Setting: We used data from...