Richard G A Faragher
Overview
Explore the profile of Richard G A Faragher including associated specialties, affiliations and a list of published articles.
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40
Citations
609
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Recent Articles
1.
Lyu Y, Fu Q, Wilczok D, Ying K, King A, Antebi A, et al.
Aging (Albany NY)
. 2024 Oct;
16(20):12955-12976.
PMID: 39418098
The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We,...
2.
Heidari N, Faragher R, Pattison G, Dudhia J, Smith R
PLoS One
. 2024 Aug;
19(8):e0309301.
PMID: 39172877
Tendinopathy is a common age-related disease which causes significant morbidity for both human athletes and performance horses. In the latter, the superficial digital flexor tendon is an excellent model for...
3.
Faragher R, Hartley R
Nat Rev Drug Discov
. 2024 May;
23(10):725-726.
PMID: 38811795
No abstract available.
4.
Tamura N, Heidari N, Faragher R, Smith R, Dudhia J
J Equine Sci
. 2023 Oct;
34(3):67-72.
PMID: 37781569
Resveratrol (RSV; trans-3,5,4'-trihydroxystilbene) strongly activates sirtuin 1, and it and its analogue V29 enhance the proliferation of mesenchymal stem/stromal cells (MSCs).Although culture medium containing 5-azacytydine and RSV inhibits senescence of...
5.
Faragher R, Heidari N, Ostler E
Subcell Biochem
. 2023 Jan;
102:175-193.
PMID: 36600134
Cellular senescence is a permanent state of growth arrest coupled with profound changes in phenotype that can be triggered by multiple extrinsic or intrinsic stimuli. Senescence is a process-level example...
6.
Cox L, Faragher R
Lancet Healthy Longev
. 2022 Sep;
3(5):e318-e320.
PMID: 36098307
No abstract available.
7.
Faragher R
Front Aging
. 2022 Jul;
2:686382.
PMID: 35822046
Cellular senescence, the irreversible growth arrest of cells from conditional renewal populations combined with a radical shift in their phenotype, is a hallmark of ageing in some mammalian species. In...
8.
Birar V, Sheerin A, Ostler E, Faragher R
Biogerontology
. 2020 Aug;
21(6):817-826.
PMID: 32793997
Resveratrol alters the cytokinetics of mammalian cell populations in a dose dependent manner. Concentrations above 25-50 µM typically trigger growth arrest, senescence and/or apoptosis in multiple different cell types. In...
9.
Faragher R, Ostler E
Gerontology
. 2020 Jan;
66(3):231-237.
PMID: 31914446
For much of the 20th century the ageing process was thought to be the result of the interplay of many different biological processes, each with relatively small effects on organismal...
10.
Bikkul M, Faragher R, Worthington G, Meinke P, Kerr A, Sammy A, et al.
Genes Chromosomes Cancer
. 2018 Nov;
58(6):341-356.
PMID: 30474255
Immortalizing primary cells with human telomerase reverse transcriptase (hTERT) has been common practice to enable primary cells to be of extended use in the laboratory because they avoid replicative senescence....