Richard A Knight
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Explore the profile of Richard A Knight including associated specialties, affiliations and a list of published articles.
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104
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6575
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Recent Articles
1.
Butera A, Agostini M, Cassandri M, De Nicola F, Fanciulli M, DAmbrosio L, et al.
Sci Adv
. 2023 Apr;
9(17):eadg5423.
PMID: 37115925
An essential function of the epidermis is to provide a physical barrier that prevents the loss of water. Essential mediators of this barrier function include ceramides, cholesterol, and very long...
2.
Panatta E, Butera A, Mammarella E, Pitolli C, Mauriello A, Leist M, et al.
Cell Rep
. 2022 Nov;
41(5):111568.
PMID: 36323249
Gene-environment interactions can perturb the epigenome, triggering network alterations that participate in cancer pathogenesis. Integrating epigenomics, transcriptomics, and metabolic analyses with functional perturbation, we show that the tumor suppressor p53...
3.
Buckley N, Panatta E, Morone N, Noguchi M, Scorrano L, Knight R, et al.
Cell Cycle
. 2020 Jun;
19(14):1833-1845.
PMID: 32584647
The p53 family transcriptional factor p73 plays a pivotal role in development. Ablation of p73 results in severe neurodevelopmental defects, chronic infections, inflammation and infertility. In addition to this, Trp73...
4.
Amelio I, Panatta E, Niklison-Chirou M, Steinert J, Agostini M, Morone N, et al.
Proc Natl Acad Sci U S A
. 2020 Jun;
117(27):15694-15701.
PMID: 32571922
The p53 family member p73 has a complex gene structure, including alternative promoters and alternative splicing of the 3' UTR. This results in a complex range of isoforms whose biological...
5.
Cassandri M, Butera A, Amelio I, Lena A, Montanaro M, Mauriello A, et al.
Oncogene
. 2020 Apr;
39(22):4331-4343.
PMID: 32313225
Breast cancer is the second leading cause of cancer-related deaths among women, largely due to the progression of a significant fraction of primary tumours to the metastatic stage. Here, we...
6.
Balamuthusamy S, Miller L, Clynes D, Kahle E, Knight R, Conway P
J Vasc Access
. 2019 Aug;
21(2):230-236.
PMID: 31464539
Objectives: To determine the vascular access modalities used for hemodialysis, the reasons for choosing them, and determinants of satisfaction with vascular access among patients with end-stage renal disease. Methods: The...
7.
Barry S, Ounzain S, McCormick J, Scarabelli T, Chen-Scarabelli C, Saravolatz L, et al.
Int J Cardiol
. 2018 Nov;
274:404.
PMID: 30449337
No abstract available.
8.
Amelio I, Mancini M, Petrova V, Cairns R, Vikhreva P, Nicolai S, et al.
Proc Natl Acad Sci U S A
. 2018 Nov;
115(46):E10869-E10878.
PMID: 30381462
Mutations in the gene and microenvironmentally driven activation of hypoxia-inducible factor-1 (HIF-1) typically occur in later stages of tumorigenesis. An ongoing challenge is the identification of molecular determinants of advanced...
9.
Pieraccioli M, Nicolai S, Pitolli C, Agostini M, Antonov A, Malewicz M, et al.
Proc Natl Acad Sci U S A
. 2018 Jun;
115(28):7356-7361.
PMID: 29941555
Derangement of cellular differentiation because of mutation or inappropriate expression of specific genes is a common feature in tumors. Here, we show that the expression of ZNF281, a zinc finger...
10.
Marini A, Rotblat B, Sbarrato T, Niklison-Chirou M, Knight J, Dudek K, et al.
Proc Natl Acad Sci U S A
. 2018 May;
115(24):6219-6224.
PMID: 29844156
TAp73 is a transcription factor that plays key roles in brain development, aging, and cancer. At the cellular level, TAp73 is a critical homeostasis-maintaining factor, particularly following oxidative stress. Although...