Richard A Knight
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Explore the profile of Richard A Knight including associated specialties, affiliations and a list of published articles.
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104
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Recent Articles
11.
Soond S, Townsend P, Barry S, Knight R, Latchman D, Stephanou A
J Biol Chem
. 2018 Apr;
293(13):4954.
PMID: 29602881
No abstract available.
12.
13.
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Galluzzi L, Vitale I, Aaronson S, Abrams J, Adam D, Agostinis P, et al.
Cell Death Differ
. 2018 Jan;
25(3):486-541.
PMID: 29362479
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from morphological, biochemical, and functional perspectives. Since the...
14.
Xie N, Vikhreva P, Annicchiarico-Petruzzelli M, Amelio I, Barlev N, Knight R, et al.
Cell Cycle
. 2017 Dec;
17(5):589-594.
PMID: 29233040
As a member of p53 family, p73 has attracted intense investigations due to its structural and functional similarities to p53. Among more than ten p73 variants, the transactivation (TA) domain-containing...
15.
Agostini M, Niklison-Chirou M, Annicchiarico-Petruzzelli M, Grelli S, Di Daniele N, Pestlikis I, et al.
Mol Neurobiol
. 2017 May;
55(4):3237-3250.
PMID: 28478509
The transcription factor p73 has been demonstrated to play a significant role in survival and differentiation of neuronal stem cells. In this report, by employing comprehensive metabolic profile and mitochondrial...
16.
Vikhreva P, Petrova V, Gokbulut T, Pestlikis I, Mancini M, Di Daniele N, et al.
Biochem Biophys Res Commun
. 2017 Feb;
482(3):498-505.
PMID: 28212736
p73 is a transcription factor belonging to the p53 tumour suppressor family. p73 mice exhibit a range of phenotypes including neurological, reproductive and inflammatory defects. Although the role of p73...
17.
Amelio I, Lisitsa A, Knight R, Melino G, Antonov A
Curr Drug Targets
. 2016 Mar;
18(5):534-543.
PMID: 26926468
The major drug discovery efforts in oncology have been concentrated on the development of selective molecules that are supposed to act specifically on one anticancer mechanism by modulating a single...
18.
Niklison-Chirou M, Killick R, Knight R, Nicotera P, Melino G, Agostini M
Mol Neurobiol
. 2015 Aug;
53(7):4509-20.
PMID: 26266644
The p53-family member, p73, plays a key role in the development of the central nervous system (CNS), in senescence, and in tumor formation. The role of p73 in neuronal differentiation...
19.
Trifonova O, Knight R, Lisitsa A, Melino G, Antonov A
Drug Discov Today
. 2015 Jul;
21(1):103-110.
PMID: 26220091
In many cases, individuality in metabolism of a drug is a reliable predictor of the drug efficacy/safety. Modern high-throughput metabolomics is an ideal instrument to track drug metabolism in an...
20.
Amelio I, Landre V, Knight R, Lisitsa A, Melino G, Antonov A
Oncotarget
. 2015 May;
6(12):9646-56.
PMID: 25991664
Targeting the ubiquitin-proteasome system (UPS) and ubiquitin-like signalling systems (UBL) has been considered a promising therapeutic strategy to treat cancer, neurodegenerative and immunological disorders. There have been multiple efforts recently...