Ricardo O Ramirez Flores
Overview
Explore the profile of Ricardo O Ramirez Flores including associated specialties, affiliations and a list of published articles.
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11
Citations
721
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Recent Articles
1.
Miyara S, Adler M, Umansky K, Haussler D, Bassat E, Divinsky Y, et al.
Cell Syst
. 2025 Feb;
:101198.
PMID: 39970910
Fibrosis remains a major unmet medical need. Simplifying principles are needed to better understand fibrosis and to yield new therapeutic approaches. Fibrosis is driven by myofibroblasts that interact with macrophages....
2.
Lerma-Martin C, Badia-I-Mompel P, Ramirez Flores R, Sekol P, Schafer P, Riedl C, et al.
Nat Neurosci
. 2024 Nov;
27(12):2354-2365.
PMID: 39501036
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. Inflammation is gradually compartmentalized and restricted to specific tissue niches such as the lesion rim. However, the...
3.
Lanzer J, Wienecke L, Ramirez Flores R, Zylla M, Kley C, Hartmann N, et al.
Basic Res Cardiol
. 2024 Sep;
119(6):1001-1028.
PMID: 39311911
Inflammation, fibrosis and metabolic stress critically promote heart failure with preserved ejection fraction (HFpEF). Exposure to high-fat diet and nitric oxide synthase inhibitor N[w]-nitro-l-arginine methyl ester (L-NAME) recapitulate features of...
4.
Muller-Dott S, Tsirvouli E, Vazquez M, Ramirez Flores R, Badia-I-Mompel P, Fallegger R, et al.
Nucleic Acids Res
. 2023 Oct;
51(20):10934-10949.
PMID: 37843125
Gene regulation plays a critical role in the cellular processes that underlie human health and disease. The regulatory relationship between transcription factors (TFs), key regulators of gene expression, and their...
5.
Badia-I-Mompel P, Wessels L, Muller-Dott S, Trimbour R, Ramirez Flores R, Argelaguet R, et al.
Nat Rev Genet
. 2023 Jun;
24(11):739-754.
PMID: 37365273
The interplay between chromatin, transcription factors and genes generates complex regulatory circuits that can be represented as gene regulatory networks (GRNs). The study of GRNs is useful to understand how...
6.
Badia-I-Mompel P, Velez Santiago J, Braunger J, Geiss C, Dimitrov D, Muller-Dott S, et al.
Bioinform Adv
. 2023 Jan;
2(1):vbac016.
PMID: 36699385
Summary: Many methods allow us to extract biological activities from omics data using information from prior knowledge resources, reducing the dimensionality for increased statistical power and better interpretability. Here, we...
7.
Frede A, Czarnewski P, Monasterio G, Tripathi K, Bejarano D, Ramirez Flores R, et al.
Immunity
. 2022 Dec;
55(12):2336-2351.e12.
PMID: 36462502
Therapeutic promotion of intestinal regeneration holds great promise, but defining the cellular mechanisms that influence tissue regeneration remains an unmet challenge. To gain insight into the process of mucosal healing,...
8.
Kuppe C, Ramirez Flores R, Li Z, Hayat S, Levinson R, Liao X, et al.
Nature
. 2022 Aug;
608(7924):766-777.
PMID: 35948637
Myocardial infarction is a leading cause of death worldwide. Although advances have been made in acute treatment, an incomplete understanding of remodelling processes has limited the effectiveness of therapies to...
9.
Dimitrov D, Turei D, Garrido-Rodriguez M, Burmedi P, Nagai J, Boys C, et al.
Nat Commun
. 2022 Jun;
13(1):3224.
PMID: 35680885
The growing availability of single-cell data, especially transcriptomics, has sparked an increased interest in the inference of cell-cell communication. Many computational tools were developed for this purpose. Each of them...
10.
Parigi S, Larsson L, Das S, Ramirez Flores R, Frede A, Tripathi K, et al.
Nat Commun
. 2022 Feb;
13(1):828.
PMID: 35149721
The intestinal barrier is composed of a complex cell network defining highly compartmentalized and specialized structures. Here, we use spatial transcriptomics to define how the transcriptomic landscape is spatially organized...