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Florian Wunnemann

Explore the profile of Florian Wunnemann including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 599
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Recent Articles
1.
Mury P, Cagnone G, Dagher O, Wunnemann F, Voghel G, Beaudoin M, et al.
JACC Basic Transl Sci . 2024 Nov; 9(10):1163-1177. PMID: 39534645
Coronary artery disease (CAD) is more prevalent in men than in women, with endothelial dysfunction, prodromal to CAD, developing a decade earlier in middle-aged men. We investigated the molecular basis...
2.
Lerma-Martin C, Badia-I-Mompel P, Ramirez Flores R, Sekol P, Schafer P, Riedl C, et al.
Nat Neurosci . 2024 Nov; 27(12):2354-2365. PMID: 39501036
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. Inflammation is gradually compartmentalized and restricted to specific tissue niches such as the lesion rim. However, the...
3.
Navarri X, Robertson D, Charfi I, Wunnemann F, Samia Fernandes do Nascimento A, Trottier G, et al.
J Neurosci . 2024 Aug; 44(41). PMID: 39214708
During adolescence, cannabis experimentation is common, and its association with interindividual variations in brain maturation well studied. Cellular and molecular underpinnings of these system-level relationships are, however, unclear. We thus...
4.
Lavertu-Jolin M, Chattopadhyaya B, Chehrazi P, Carrier D, Wunnemann F, Leclerc S, et al.
Mol Psychiatry . 2023 May; 28(7):2946-2963. PMID: 37131076
While persistence of fear memories is essential for survival, a failure to inhibit fear in response to harmless stimuli is a feature of anxiety disorders. Extinction training only temporarily suppresses...
5.
Wunnemann F, Fotsing Tadjo T, Beaudoin M, Lalonde S, Lo K, Kleinstiver B, et al.
PLoS Genet . 2023 Mar; 19(3):e1010680. PMID: 36928188
Genome-wide association studies have identified >250 genetic variants associated with coronary artery disease (CAD), but the causal variants, genes and molecular mechanisms remain unknown at most loci. We performed pooled...
6.
Churakov G, Kuritzin A, Chukharev K, Zhang F, Wunnemann F, Ulyantsev V, et al.
Syst Biol . 2023 Jan; 72(3):649-661. PMID: 36688484
Retrophylogenomics makes use of genome-wide retrotransposon presence/absence insertion patterns to resolve questions in phylogeny and population genetics. In the genomics era, evaluating high-throughput data requires the associated development of appropriately...
7.
Kuppe C, Ramirez Flores R, Li Z, Hayat S, Levinson R, Liao X, et al.
Nature . 2022 Aug; 608(7924):766-777. PMID: 35948637
Myocardial infarction is a leading cause of death worldwide. Although advances have been made in acute treatment, an incomplete understanding of remodelling processes has limited the effectiveness of therapies to...
8.
Biermann J, Melms J, Amin A, Wang Y, Caprio L, Karz A, et al.
Cell . 2022 Jul; 185(14):2591-2608.e30. PMID: 35803246
Melanoma brain metastasis (MBM) frequently occurs in patients with advanced melanoma; yet, our understanding of the underlying salient biology is rudimentary. Here, we performed single-cell/nucleus RNA-seq in 22 treatment-naive MBMs...
9.
Heckel E, Cagnone G, Agnihotri T, Cakir B, Das A, Kim J, et al.
JCI Insight . 2022 Feb; 7(6). PMID: 35167498
Dyslipidemia and autophagy have been implicated in the pathogenesis of blinding neovascular age-related macular degeneration (NV-AMD). VLDL receptor (VLDLR), expressed in photoreceptors with a high metabolic rate, facilitates the uptake...
10.
Audain E, Wilsdon A, Breckpot J, Izarzugaza J, Fitzgerald T, Kahlert A, et al.
PLoS Genet . 2021 Sep; 17(9):e1009809. PMID: 34547032
[This corrects the article DOI: 10.1371/journal.pgen.1009679.].