Ricardo Nunes Bastos
Overview
Explore the profile of Ricardo Nunes Bastos including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
937
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Recent Articles
1.
Wang Y, Buck A, Piel B, Zerefa L, Murugan N, Coherd C, et al.
Mol Cancer
. 2024 Mar;
23(1):56.
PMID: 38491381
One of the major hurdles that has hindered the success of chimeric antigen receptor (CAR) T cell therapies against solid tumors is on-target off-tumor (OTOT) toxicity due to sharing of...
2.
He Y, De Grandi D, Chandradoss S, Lutheryn G, Cidonio G, Bastos R, et al.
Micromachines (Basel)
. 2023 Sep;
14(9).
PMID: 37763926
Nanoscale liposomes have been extensively researched and employed clinically for the delivery of biologically active compounds, including chemotherapy drugs and vaccines, offering improved pharmacokinetic behaviour and therapeutic outcomes. Traditional laboratory-scale...
3.
Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle
Serena M, Bastos R, Elliott P, Barr F
J Cell Biol
. 2020 May;
219(7).
PMID: 32356865
The Aurora B chromosomal passenger complex (CPC) is a conserved regulator of mitosis. Its functions require localization first to the chromosome arms and then centromeres in mitosis and subsequently the...
4.
Louw J, Bastos R, Chen X, Verdood C, Corveleyn A, Jia Y, et al.
PLoS Genet
. 2018 Jan;
14(1):e1007138.
PMID: 29357359
Congenital or neonatal cardiomyopathies are commonly associated with a poor prognosis and have multiple etiologies. In two siblings, a male and female, we identified an undescribed type of lethal congenital...
5.
Beaven R, Bastos R, Spanos C, Rome P, Cullen C, Rappsilber J, et al.
J Cell Biol
. 2017 Sep;
216(10):3029-3039.
PMID: 28860275
The meiotic spindle is formed without centrosomes in a large volume of oocytes. Local activation of crucial spindle proteins around chromosomes is important for formation and maintenance of a bipolar...
6.
Cundell M, Hutter L, Bastos R, Poser E, Holder J, Mohammed S, et al.
J Cell Biol
. 2016 Aug;
214(5):539-54.
PMID: 27551054
PP2A-B55 is one of the major phosphatases regulating cell division. Despite its importance for temporal control during mitotic exit, how B55 substrates are recognized and differentially dephosphorylated is unclear. Using...
7.
Bastos R, Cundell M, Barr F
J Cell Biol
. 2014 Dec;
207(6):683-93.
PMID: 25512391
The mitotic kinase Aurora B is concentrated at the anaphase central spindle by the kinesin MKlp2 during mitotic exit and cytokinesis. This pool of Aurora B phosphorylates substrates including the...
8.
Espert A, Uluocak P, Bastos R, Mangat D, Graab P, Gruneberg U
J Cell Biol
. 2014 Sep;
206(7):833-42.
PMID: 25246613
The spindle assembly checkpoint (SAC) monitors correct attachment of chromosomes to microtubules, an important safeguard mechanism ensuring faithful chromosome segregation in eukaryotic cells. How the SAC signal is turned off...
9.
Gerondopoulos A, Bastos R, Yoshimura S, Anderson R, Carpanini S, Aligianis I, et al.
J Cell Biol
. 2014 Jun;
205(5):707-20.
PMID: 24891604
The ancestral Rab GTPase Rab18 and both subunits of the Rab3GAP complex are mutated in the human neurological and developmental disorder Warburg Micro syndrome. Here, we demonstrate that the Rab3GAP...
10.
Langemeyer L, Bastos R, Cai Y, Itzen A, Reinisch K, Barr F
Elife
. 2014 Feb;
3:e01623.
PMID: 24520163
Ras superfamily GTPase activation and inactivation occur by canonical nucleotide exchange and GTP hydrolysis mechanisms. Despite conservation of active-site residues, the Ras-related Rab GTPase activation pathway differs from Ras and...