Shin-Ichiro Yoshimura
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Explore the profile of Shin-Ichiro Yoshimura including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
2149
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Recent Articles
1.
Zhang Y, Kunii M, Taniguchi M, Yoshimura S, Harada A
J Neurosci
. 2024 Jun;
44(27).
PMID: 38830762
Neurons are highly polarized cells that are composed of a single axon and multiple dendrites. Axon-dendrite polarity is essential for proper tissue formation and brain functions. Intracellular protein transport plays...
2.
Harada A, Kunii M, Kurokawa K, Sumi T, Kanda S, Zhang Y, et al.
Nat Commun
. 2024 May;
15(1):4514.
PMID: 38802491
Knowledge on the distribution and dynamics of glycosylation enzymes in the Golgi is essential for better understanding this modification. Here, using a combination of CRISPR/Cas9 knockin technology and super-resolution microscopy,...
3.
Wu J, Moriwaki K, Asuka T, Nakai R, Kanda S, Taniguchi M, et al.
Blood Adv
. 2023 Apr;
7(14):3382-3394.
PMID: 37042948
Cell polarity, the asymmetric distribution of proteins and organelles, is permanently or transiently established in various cell types and plays an important role in many physiological events. epidermal growth factor...
4.
Iwano T, Sobajima T, Takeda S, Harada A, Yoshimura S
J Biol Chem
. 2023 Feb;
299(3):102985.
PMID: 36754282
Primary cilia are organelles consisting of axonemal microtubules and plasma membranes, and they protrude from the cell surface to the extracellular region and function in signal sensing and transduction. The...
5.
Tsujimoto K, Jo T, Nagira D, Konaka H, Park J, Yoshimura S, et al.
EMBO J
. 2022 Nov;
42(1):e111389.
PMID: 36444797
The cellular activation of the NLRP3 inflammasome is spatiotemporally orchestrated by various organelles, but whether lysosomes contribute to this process remains unclear. Here, we show the vital role of the...
6.
Oe Y, Kakuda K, Yoshimura S, Hara N, Hasegawa J, Terawaki S, et al.
PLoS Genet
. 2022 Jun;
18(6):e1010264.
PMID: 35771772
Autophagy is an indispensable process that degrades cytoplasmic materials to maintain cellular homeostasis. During autophagy, double-membrane autophagosomes surround cytoplasmic materials and either fuse with endosomes (called amphisomes) and then lysosomes,...
7.
Kunii M, Noguchi Y, Yoshimura S, Kanda S, Iwano T, Avriyanti E, et al.
J Cell Biol
. 2020 Dec;
220(1).
PMID: 33332551
In the developing brain, the polarity of neural progenitor cells, termed radial glial cells (RGCs), is important for neurogenesis. Intercellular adhesions, termed apical junctional complexes (AJCs), at the apical surface...
8.
Iwaki A, Moriwaki K, Sobajima T, Taniguchi M, Yoshimura S, Kunii M, et al.
FASEB J
. 2020 Jun;
34(7):9450-9465.
PMID: 32496646
Intestinal epithelial cells (IECs) are not only responsible for the digestion and absorption of dietary substrates but also function as a first line of host defense against commensal and pathogenic...
9.
Miyazaki A, Yoshimura S, Matsutani H, Miyake M, Negishi J, Yamanaka K, et al.
Cardiol Young
. 2019 Sep;
29(11):1375-1379.
PMID: 31507257
Background: Atrioventricular interval optimisation is important in patients with dual-chamber pacing, especially with heart failure. In patients with CHD, especially in those with Fontan circulation, the systemic atrial contraction is...
10.
Eguchi T, Kuwahara T, Sakurai M, Komori T, Fujimoto T, Ito G, et al.
Proc Natl Acad Sci U S A
. 2018 Sep;
115(39):E9115-E9124.
PMID: 30209220
Leucine-rich repeat kinase 2 () has been associated with a variety of human diseases, including Parkinson's disease and Crohn's disease, whereas deficiency leads to accumulation of abnormal lysosomes in aged...