Ricardo A Cordova
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Explore the profile of Ricardo A Cordova including associated specialties, affiliations and a list of published articles.
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9
Citations
69
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Recent Articles
1.
Qiang H, Wang F, Lu W, Xing X, Kim H, Merette S, et al.
bioRxiv
. 2024 Nov;
PMID: 39605668
Despite decades of study, large parts of the mammalian metabolome remain unexplored. Mass spectrometry-based metabolomics routinely detects thousands of small molecule-associated peaks within human tissues and biofluids, but typically only...
2.
Cordova R, Sommers N, Law A, Klunk A, Brady K, Goodrich D, et al.
Sci Signal
. 2024 Nov;
17(864):eadp1375.
PMID: 39591412
Cancers invoke various pathways to mitigate external and internal stresses to continue their growth and progression. We previously reported that the eIF2 kinase GCN2 and the integrated stress response are...
3.
Damayanti N, Cordova R, Rupert C, Delle Fontane I, Shen L, Orsi S, et al.
Cancer Res
. 2024 Jan;
84(8):1286-1302.
PMID: 38266162
Significance: TFE3-splicing factor fusions possess both transcription and splicing factor functions that remodel the transcriptome and spliceosome and can be targeted with dimerization inhibitors to suppress the growth of translocation...
4.
Mijit M, Boner M, Cordova R, Gampala S, Kpenu E, Klunk A, et al.
Front Med (Lausanne)
. 2023 May;
10:1146115.
PMID: 37181357
Pancreatic cancer or pancreatic ductal adenocarcinoma (PDAC) is characterized by a profound inflammatory tumor microenvironment (TME) with high heterogeneity, metastatic propensity, and extreme hypoxia. The integrated stress response (ISR) pathway...
5.
Jin D, Wek S, Cordova R, Wek R, Lacombe D, Michaud V, et al.
Clin Genet
. 2022 Nov;
103(3):358-363.
PMID: 36411955
Aminoacyl-tRNA synthetases are enzymes that ensure accurate protein synthesis. Variants of the dual-functional cytoplasmic human glutamyl-prolyl-tRNA synthetase, EPRS1, have been associated with leukodystrophy, diabetes and bone disease. Here, we report...
6.
Cordova R, Misra J, Amin P, Klunk A, Damayanti N, Carlson K, et al.
Elife
. 2022 Sep;
11.
PMID: 36107759
A stress adaptation pathway termed the integrated stress response has been suggested to be active in many cancers including prostate cancer (PCa). Here, we demonstrate that the eIF2 kinase GCN2...
7.
Sabbagh J, Cordova R, Zheng D, Criado-Marrero M, Lemus A, Li P, et al.
ACS Chem Biol
. 2018 Jun;
13(8):2288-2299.
PMID: 29893552
Genetic and epigenetic alterations in FK506-binding protein 5 ( FKBP5) have been associated with increased risk for psychiatric disorders, including post-traumatic stress disorder (PTSD). Some of these common variants can...
8.
Huard D, Crowley V, Du Y, Cordova R, Sun Z, Tomlin M, et al.
ACS Chem Biol
. 2018 Feb;
13(4):933-941.
PMID: 29402077
Gain-of-function mutations within the olfactomedin (OLF) domain of myocilin result in its toxic intracellular accumulation and hasten the onset of open-angle glaucoma. The absence of myocilin does not cause disease;...
9.
Munoz E, Schrebler R, Cury P, Suarez C, Cordova R, Gomez C, et al.
J Phys Chem B
. 2006 Oct;
110(42):21109-17.
PMID: 17048933
In this study, we examined the influence of illumination and the presence of poly(ethylene oxide) (PEO) as an additive for the copper electrodeposition process onto n-Si(100). The study was carried...