Reynand Pacoma
Overview
Explore the profile of Reynand Pacoma including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
62
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0
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Recent Articles
1.
Cheng H, Deaton L, Qiu M, Ha S, Pacoma R, Lao J, et al.
Neurobiol Dis
. 2019 Nov;
134:104683.
PMID: 31765727
Repeated mild traumatic brain injury (rmTBI) can lead to development of chronic traumatic encephalopathy (CTE), which is characterized by progressive neurodegeneration with presence of white matter damage, gliosis and hyper-phosphorylated...
2.
Cheung S, Miller M, Pacoma R, Roland J, Liu J, Schumacher A, et al.
ACS Chem Biol
. 2017 Nov;
12(12):3126-3133.
PMID: 29099173
Glycosaminoglycans (GAGs) play critical roles in diverse processes ranging from viral infection to neuroregeneration. Their regiospecific sulfation patterns, which are generated by sulfotransferases, are key structural determinants that underlie their...
3.
Walker J, Pacoma R, Watson J, Ou W, Alves J, Mason D, et al.
J Neurosci
. 2013 Feb;
33(6):2457-64.
PMID: 23392674
Accumulation of β-amyloid (Aβ) in the brain is believed to contribute to the pathology of Alzheimer's Disease (AD). Aβ levels are controlled by the production of Aβ from amyloid precursor...
4.
Tully D, Vidal A, Chatterjee A, Williams J, Roberts M, Petrassi H, et al.
Bioorg Med Chem Lett
. 2008 Aug;
18(22):5895-9.
PMID: 18752942
Structure-based design was utilized to guide the early stage optimization of a substrate-like inhibitor to afford potent peptidomimetic inhibitors of the channel-activating protease prostasin. The first X-ray crystal structures of...