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Reshma S Baliga

Explore the profile of Reshma S Baliga including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 508
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Recent Articles
1.
Lowe V, Aubdool A, Moyes A, Dignam J, Perez-Ternero C, Baliga R, et al.
Pharmacol Res . 2024 Oct; 209:107447. PMID: 39374886
Background: C-type natriuretic peptide (CNP) is a significant player in the maintenance of cardiac and vascular homeostasis regulating local blood flow, platelet and leukocyte activation, heart structure and function, angiogenesis...
2.
Papaioannou I, Dritsoula A, Kang P, Baliga R, Trinder S, Cook E, et al.
JCI Insight . 2024 Apr; 9(10). PMID: 38652537
NKX2-5 is a member of the homeobox-containing transcription factors critical in regulating tissue differentiation in development. Here, we report a role for NKX2-5 in vascular smooth muscle cell phenotypic modulation...
3.
Grange R, Preedy M, Renukanthan A, Dignam J, Lowe V, Moyes A, et al.
Br J Pharmacol . 2021 Jun; 179(11):2443-2459. PMID: 34131904
Background And Purpose: cGMP underpins the bioactivity of NO and natriuretic peptides and is key to cardiovascular homeostasis. cGMP-driven responses are terminated primarily by PDEs, but cellular efflux via multidrug...
4.
Preedy M, Baliga R, Hobbs A
J Cardiovasc Pharmacol . 2019 Sep; 75(5):370-384. PMID: 31498237
Heart failure (HF) is a common consequence of several cardiovascular diseases and is understood as a vicious cycle of cardiac and hemodynamic decline. The current inventory of treatments either alleviates...
5.
Dukinfield M, Maniati E, Reynolds L, Aubdool A, Baliga R, DAmico G, et al.
J Pathol . 2019 Aug; 249(4):523-535. PMID: 31424556
Coronary microvascular dysfunction combined with maladaptive cardiomyocyte morphology and energetics is a major contributor to heart failure advancement. Thus, dually enhancing cardiac angiogenesis and targeting cardiomyocyte function to slow, or...
6.
Moyes A, Chu S, Aubdool A, Dukinfield M, Margulies K, Bedi K, et al.
Eur Heart J . 2019 Mar; 41(9):1006-1020. PMID: 30903134
Aims: C-type natriuretic peptide (CNP) is an essential endothelium-derived signalling species that governs vascular homoeostasis; CNP is also expressed in the heart but an intrinsic role for the peptide in...
7.
Hobbs A, Moyes A, Baliga R, Ghedia D, Ochiel R, Sylvestre Y, et al.
Br J Pharmacol . 2019 Feb; 176(9):1251-1267. PMID: 30761523
Background And Purpose: Pulmonary arterial hypertension (PAH) is an incurable, incapacitating disorder resulting from increased pulmonary vascular resistance, pulmonary arterial remodelling, and right ventricular failure. In preclinical models, the combination...
8.
Baliga R, Preedy M, Dukinfield M, Chu S, Aubdool A, Bubb K, et al.
Proc Natl Acad Sci U S A . 2018 Jul; 115(31):E7428-E7437. PMID: 30012589
Heart failure (HF) is a shared manifestation of several cardiovascular pathologies, including hypertension and myocardial infarction, and a limited repertoire of treatment modalities entails that the associated morbidity and mortality...
9.
Moyes A, Khambata R, Villar I, Bubb K, Baliga R, Lumsden N, et al.
J Clin Invest . 2014 Aug; 124(9):4039-51. PMID: 25105365
The endothelium plays a fundamental role in maintaining vascular homeostasis by releasing factors that regulate local blood flow, systemic blood pressure, and the reactivity of leukocytes and platelets. Accordingly, endothelial...
10.
Bubb K, Trinder S, Baliga R, Patel J, Clapp L, MacAllister R, et al.
Circulation . 2014 Jun; 130(6):496-507. PMID: 24899690
Background: Pulmonary hypertension (PH) is a life-threatening disorder characterized by increased pulmonary artery pressure, remodeling of the pulmonary vasculature, and right ventricular failure. Loss of endothelium-derived nitric oxide (NO) and...