Amie J Moyes
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Explore the profile of Amie J Moyes including associated specialties, affiliations and a list of published articles.
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17
Citations
286
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Recent Articles
1.
Lowe V, Aubdool A, Moyes A, Dignam J, Perez-Ternero C, Baliga R, et al.
Pharmacol Res
. 2024 Oct;
209:107447.
PMID: 39374886
Background: C-type natriuretic peptide (CNP) is a significant player in the maintenance of cardiac and vascular homeostasis regulating local blood flow, platelet and leukocyte activation, heart structure and function, angiogenesis...
2.
Dickinson Y, Moyes A, Hobbs A
Pharmacol Ther
. 2024 Aug;
262:108708.
PMID: 39154787
C-type natriuretic peptide (CNP) represents the 'local' member of the natriuretic peptide family, functioning in an autocrine or paracrine capacity to modulate a hugely diverse portfolio of physiological processes. Whilst...
3.
Perez-Ternero C, Aubdool A, Makwana R, Sanger G, Stimson R, Chan L, et al.
Proc Natl Acad Sci U S A
. 2022 Mar;
119(13):e2116470119.
PMID: 35333648
Thermogenesis and adipogenesis are tightly regulated mechanisms that maintain lipid homeostasis and energy balance; dysfunction of these critical processes underpins obesity and contributes to cardiometabolic disease. C-type natriuretic peptide (CNP)...
4.
Grange R, Preedy M, Renukanthan A, Dignam J, Lowe V, Moyes A, et al.
Br J Pharmacol
. 2021 Jun;
179(11):2443-2459.
PMID: 34131904
Background And Purpose: cGMP underpins the bioactivity of NO and natriuretic peptides and is key to cardiovascular homeostasis. cGMP-driven responses are terminated primarily by PDEs, but cellular efflux via multidrug...
5.
Aziz Q, Chen J, Moyes A, Li Y, Anderson N, Ang R, et al.
J Mol Med (Berl)
. 2020 Jul;
98(8):1149-1160.
PMID: 32632751
K channels in the vasculature composed of Kir6.1 regulate vascular tone and may contribute to the pathogenesis of endotoxemia. We used mice with cell-specific deletion of Kir6.1 in smooth muscle...
6.
Moyes A, Hobbs A
Int J Mol Sci
. 2019 May;
20(9).
PMID: 31072047
C-type natriuretic peptide (CNP) is an autocrine and paracrine mediator released by endothelial cells, cardiomyocytes and fibroblasts that regulates vital physiological functions in the cardiovascular system. These roles are conveyed...
7.
Moyes A, Chu S, Aubdool A, Dukinfield M, Margulies K, Bedi K, et al.
Eur Heart J
. 2019 Mar;
41(9):1006-1020.
PMID: 30903134
Aims: C-type natriuretic peptide (CNP) is an essential endothelium-derived signalling species that governs vascular homoeostasis; CNP is also expressed in the heart but an intrinsic role for the peptide in...
8.
Hobbs A, Moyes A, Baliga R, Ghedia D, Ochiel R, Sylvestre Y, et al.
Br J Pharmacol
. 2019 Feb;
176(9):1251-1267.
PMID: 30761523
Background And Purpose: Pulmonary arterial hypertension (PAH) is an incurable, incapacitating disorder resulting from increased pulmonary vascular resistance, pulmonary arterial remodelling, and right ventricular failure. In preclinical models, the combination...
9.
Bubb K, Aubdool A, Moyes A, Lewis S, Drayton J, Tang O, et al.
Circulation
. 2018 Dec;
139(13):1612-1628.
PMID: 30586761
Background: Angiogenesis and vascular remodeling are complementary, innate responses to ischemic cardiovascular events, including peripheral artery disease and myocardial infarction, which restore tissue blood supply and oxygenation; the endothelium plays...
10.
Baliga R, Preedy M, Dukinfield M, Chu S, Aubdool A, Bubb K, et al.
Proc Natl Acad Sci U S A
. 2018 Jul;
115(31):E7428-E7437.
PMID: 30012589
Heart failure (HF) is a shared manifestation of several cardiovascular pathologies, including hypertension and myocardial infarction, and a limited repertoire of treatment modalities entails that the associated morbidity and mortality...