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Renaud Vandenbosch

Explore the profile of Renaud Vandenbosch including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 529
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Recent Articles
1.
Schumacher N, Vandenbosch R, Franzen R
J Neurochem . 2024 Dec; 169(1):e16268. PMID: 39655795
Peripheral myelin is synthesized by glial cells called Schwann cells (SCs). SC development and differentiation must be tightly regulated to avoid any pathological consequence affecting peripheral nerve function. Neuropathic symptoms...
2.
Daes T, Marlier Q, Verteneuil S, Quatresooz P, Vandenbosch R, Malgrange B
Int J Mol Sci . 2023 Apr; 24(8). PMID: 37108171
Previous research has shown that cyclin-dependent kinases (Cdks) that play physiological roles in cell cycle regulation become activated in post-mitotic neurons after ischemic stroke, resulting in apoptotic neuronal death. In...
3.
Fong B, Chakroun I, Iqbal M, Paul S, Bastasic J, ONeil D, et al.
Cell Rep . 2022 Nov; 41(5):111578. PMID: 36323247
Long-term maintenance of the adult neurogenic niche depends on proper regulation of entry and exit from quiescence. Neural stem cell (NSC) transition from quiescence to activation is a complex process...
4.
Dion V, Schumacher N, Masar N, Pieltain A, Tocquin P, Lesoinne P, et al.
Glia . 2022 Apr; 70(9):1652-1665. PMID: 35488490
Mechanisms regulating oligodendrocyte differentiation, developmental myelination and myelin maintenance in adulthood are complex and still not completely described. Their understanding is crucial for the development of new protective or therapeutic...
5.
Marlier Q, Daes T, Verteneuil S, Vandenbosch R, Malgrange B
Cell Mol Life Sci . 2020 Jun; 77(22):4553-4571. PMID: 32476056
A persistent dogma in neuroscience supported the idea that terminally differentiated neurons permanently withdraw from the cell cycle. However, since the late 1990s, several studies have shown that cell cycle...
6.
Caron N, Genin E, Marlier Q, Verteneuil S, Beukelaers P, Morel L, et al.
Cell Mol Life Sci . 2018 May; 75(20):3817-3827. PMID: 29728713
Neural stem cells give rise to granule dentate neurons throughout life in the hippocampus. Upon activation, these stem cells generate fast proliferating progenitors that complete several rounds of divisions before...
7.
Marlier Q, Jibassia F, Verteneuil S, Linden J, Kaldis P, Meijer L, et al.
Cell Death Discov . 2018 Mar; 4:43. PMID: 29581894
Cell cycle proteins are mainly expressed by dividing cells. However, it is well established that these molecules play additional non-canonical activities in several cell death contexts. Increasing evidence shows expression...
8.
Vandenbosch R, Clark A, Fong B, Omais S, Jaafar C, Dugal-Tessier D, et al.
Hippocampus . 2016 Jun; 26(11):1379-1392. PMID: 27325572
In mammals, hippocampal dentate gyrus granule cells (DGCs) constitute a particular neuronal population produced both during embryogenesis and adult life, and play key roles in neural plasticity and memory. However,...
9.
Naser R, Vandenbosch R, Omais S, Hayek D, Jaafar C, Al Lafi S, et al.
Sci Rep . 2016 Feb; 6:20230. PMID: 26847607
Adult neural stem cells (aNSCs) are relatively quiescent populations that give rise to distinct neuronal subtypes throughout life, yet, at a very low rate and restricted differentiation potential. Thus, identifying...
10.
Marlier Q, Verteneuil S, Vandenbosch R, Malgrange B
Front Neurosci . 2015 Dec; 9:458. PMID: 26696816
Stroke affects one in every six people worldwide, and is the leading cause of adult disability. After stroke, some limited spontaneous recovery occurs, the mechanisms of which remain largely unknown....