Brigitte Malgrange
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Explore the profile of Brigitte Malgrange including associated specialties, affiliations and a list of published articles.
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75
Citations
1874
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Recent Articles
1.
Presse M, Malgrange B, Delacroix L
Matrix Biol
. 2023 Dec;
125:40-58.
PMID: 38070832
The extracellular matrix (ECM) consists in a complex meshwork of collagens, glycoproteins, and proteoglycans, which serves a scaffolding function and provides viscoelastic properties to the tissues. ECM acts as a...
2.
Veithen M, Huyghe A, Van Den Ackerveken P, Fukada S, Kokubo H, Breuskin I, et al.
Cells
. 2023 Sep;
12(17).
PMID: 37681879
It is widely accepted that cell fate determination in the cochlea is tightly controlled by different transcription factors (TFs) that remain to be fully defined. Here, we show that Sox9,...
3.
Chohra I, Giri S, Malgrange B
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37445725
The chromatin remodeler Chromodomain-helicase-DNA-binding protein 4 (CHD4) is crucial for the development of multiple organ systems. Functional mutations of CHD4 have recently been described in a developmental disorder, namely Siffrim-Hitz-Weiss...
4.
Daes T, Marlier Q, Verteneuil S, Quatresooz P, Vandenbosch R, Malgrange B
Int J Mol Sci
. 2023 Apr;
24(8).
PMID: 37108171
Previous research has shown that cyclin-dependent kinases (Cdks) that play physiological roles in cell cycle regulation become activated in post-mitotic neurons after ischemic stroke, resulting in apoptotic neuronal death. In...
5.
Chohra I, Chung K, Giri S, Malgrange B
Cells
. 2023 Feb;
12(4).
PMID: 36831199
During transcription, DNA replication and repair, chromatin structure is constantly modified to reveal specific genetic regions and allow access to DNA-interacting enzymes. ATP-dependent chromatin remodelling complexes use the energy of...
6.
Malgrange B, Nguyen L
Science
. 2022 Sep;
377(6611):1155-1156.
PMID: 36074827
A genetic change could explain increased cortical neurogenesis in modern humans.
7.
Dion V, Schumacher N, Masar N, Pieltain A, Tocquin P, Lesoinne P, et al.
Glia
. 2022 Apr;
70(9):1652-1665.
PMID: 35488490
Mechanisms regulating oligodendrocyte differentiation, developmental myelination and myelin maintenance in adulthood are complex and still not completely described. Their understanding is crucial for the development of new protective or therapeutic...
8.
Pouyo R, Chung K, Delacroix L, Malgrange B
Hear Res
. 2021 Oct;
426:108366.
PMID: 34645583
Post-translational modifications of proteins are essential for the proper development and function of many tissues and organs, including the inner ear. Ubiquitination is a highly selective post-translational modification that involves...
9.
Renauld J, Thelen N, Bartholome O, Malgrange B, Thiry M
Cell Struct Funct
. 2021 Jan;
46(1):11-20.
PMID: 33473065
The development of hearing in mammals requires the formation and maturation of a highly organized and specialized epithelium known as the organ of Corti. This epithelium contains two types of...
10.
Marlier Q, Daes T, Verteneuil S, Vandenbosch R, Malgrange B
Cell Mol Life Sci
. 2020 Jun;
77(22):4553-4571.
PMID: 32476056
A persistent dogma in neuroscience supported the idea that terminally differentiated neurons permanently withdraw from the cell cycle. However, since the late 1990s, several studies have shown that cell cycle...