Renan Escalante-Chong
Overview
Explore the profile of Renan Escalante-Chong including associated specialties, affiliations and a list of published articles.
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12
Citations
497
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Recent Articles
1.
Matlock A, Vaibhav V, Holewinski R, Venkatraman V, Dardov V, Manalo D, et al.
Sci Data
. 2023 Jan;
10(1):24.
PMID: 36631473
The National Institute of Health (NIH) Library of integrated network-based cellular signatures (LINCS) program is premised on the generation of a publicly available data resource of cell-based biochemical responses or...
2.
Li J, Lim R, Kaye J, Dardov V, Coyne A, Wu J, et al.
iScience
. 2021 Nov;
24(11):103221.
PMID: 34746695
Neurodegenerative diseases are challenging for systems biology because of the lack of reliable animal models or patient samples at early disease stages. Induced pluripotent stem cells (iPSCs) could address these...
3.
Kim J, Kusko R, Zeskind B, Zhang J, Escalante-Chong R
Biochim Biophys Acta Rev Cancer
. 2021 Apr;
1876(1):188548.
PMID: 33901609
Background: The concurrent growth of large-scale oncology data alongside the computational methods with which to analyze and model it has created a promising environment for revolutionizing cancer diagnosis, treatment, prevention,...
4.
Kusko R, Dreymann J, Ross J, Cha Y, Escalante-Chong R, Garcia-Miralles M, et al.
Mol Neurodegener
. 2018 May;
13(1):25.
PMID: 29783994
Background: Huntington Disease (HD) is an incurable autosomal dominant neurodegenerative disorder driven by an expansion repeat giving rise to the mutant huntingtin protein (mHtt), which is known to disrupt a...
5.
Brothers 2nd J, Ung M, Escalante-Chong R, Ross J, Zhang J, Cha Y, et al.
Biochem Pharmacol
. 2018 Mar;
152:84-93.
PMID: 29551586
The tremendous expansion of data analytics and public and private big datasets presents an important opportunity for pre-clinical drug discovery and development. In the field of life sciences, the growth...
6.
Keenan A, Jenkins S, Jagodnik K, Koplev S, He E, Torre D, et al.
Cell Syst
. 2017 Dec;
6(1):13-24.
PMID: 29199020
The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common Fund program that catalogs how human cells globally respond to chemical, genetic, and disease perturbations. Resources generated by...
7.
Marquardt S, Escalante-Chong R, Pho N, Wang J, Churchman L, Springer M, et al.
Cell
. 2017 Sep;
158(2):462.
PMID: 28915368
No abstract available.
8.
Lee K, Wang J, Palme J, Escalante-Chong R, Hua B, Springer M
PLoS Genet
. 2017 May;
13(5):e1006766.
PMID: 28542190
In nature, microbes often need to "decide" which of several available nutrients to utilize, a choice that depends on a cell's inherent preference and external nutrient levels. While natural environments...
9.
Milani P, Escalante-Chong R, Shelley B, Patel-Murray N, Xin X, Adam M, et al.
Sci Rep
. 2016 May;
6:25474.
PMID: 27146274
In recent years, the assay for transposase-accessible chromatin using sequencing (ATAC-Seq) has become a fundamental tool of epigenomic research. However, it is difficult to perform this technique on frozen samples...
10.
Wang J, Atolia E, Hua B, Savir Y, Escalante-Chong R, Springer M
PLoS Biol
. 2015 Jan;
13(1):e1002041.
PMID: 25626068
Maximizing growth and survival in the face of a complex, time-varying environment is a common problem for single-celled organisms in the wild. When offered two different sugars as carbon sources,...