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Remy Pedeux

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Articles 52
Citations 1013
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Recent Articles
1.
Jarry U, Bostoen M, Archambeau J, Pineau R, Chaillot L, Jouan F, et al.
PLoS One . 2024 Jun; 19(6):e0304914. PMID: 38935790
Lung cancer is one of the most common and deadliest cancers. Preclinical models are essential to study new therapies and combinations taking tumor genetics into account. We have established cell...
2.
Yaacoub K, Pedeux R, Lafite P, Jarry U, Aci-Seche S, Bonnet P, et al.
Curr Issues Mol Biol . 2024 Jan; 46(1):710-728. PMID: 38248348
The catalytically inactive caspase-8-homologous protein, c-FLIP, is a potent antiapoptotic protein highly expressed in various types of cancers. c-FLIP competes with caspase-8 for binding to the adaptor protein FADD (Fas-Associated...
3.
Iglicki D, Kahn M, Goubault C, Blot M, Jarry U, Pedeux R, et al.
Int J Pharm . 2023 Dec; 649:123645. PMID: 38040393
Drug nanocapsules coated with iron oxide nanoparticles (SPION) were elaborated by the simultaneous nanoprecipitation of the drug and the nanoparticles, through solvent shifting. We examined four drugs: sorafenib, sorafenib tosylate,...
4.
Ricordel C, Chaillot L, Vlachavas E, Logotheti M, Jouannic A, Desvallees T, et al.
Sci Rep . 2023 Mar; 13(1):3626. PMID: 36869231
Circulating tumor cells (CTC) have been studied in various solid tumors but clinical utility of CTC in small cell lung cancer (SCLC) remains unclear. The aim of the CTC-CPC study...
5.
Almada L, Barroso K, Sen S, Toruner M, Sigafoos A, Raja Arul G, et al.
Biochim Biophys Acta Gene Regul Mech . 2023 Feb; 1866(2):194924. PMID: 36842643
Upon accumulation of improperly folded proteins in the Endoplasmic Reticulum (ER), the Unfolded Protein Response (UPR) is triggered to restore ER homeostasis. The induction of stress genes is a sine...
6.
Heliez L, Ricordel C, Becuwe P, Pedeux R
Curr Opin Pharmacol . 2022 Dec; 68:102324. PMID: 36521226
The INhibitor of Growth (ING) proteins (ING1, ING2, ING3, ING4 and ING5) are a family of epigenetic regulators. Their decreased expression in numerous cancers led to identifying the ING proteins...
7.
Gutierrez C, Pinson X, Jarnouen K, Charpentier M, Pineau R, Lallement L, et al.
Cancers (Basel) . 2022 May; 14(9). PMID: 35565300
Urine cytology is non-invasive, easy to collect, with medium sensitivity and a high specificity. It is an effective way to detect high-grade bladder cancer (BC), but it is less effective...
8.
Mahfoudhi E, Ricordel C, Lecuyer G, Mouric C, Lena H, Pedeux R
Front Oncol . 2022 Apr; 12:853501. PMID: 35463360
Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are currently recommended as first-line treatment for advanced non-small-cell lung cancer (NSCLC) with -activating mutations. Third-generation (3rd G) EGFR-TKIs, including osimertinib, offer...
9.
Papaioannou A, Centonze F, Metais A, Maurel M, Negroni L, Gonzalez-Quiroz M, et al.
Life Sci Alliance . 2022 Feb; 5(5). PMID: 35193953
ER stress is mediated by three sensors and the most evolutionary conserved IRE1α signals through its cytosolic kinase and endoribonuclease (RNase) activities. IRE1α RNase activity can either catalyze the initial...
10.
Goubault C, Jarry U, Bostoen M, Eliat P, Kahn M, Pedeux R, et al.
Nanomedicine . 2021 Nov; 40:102499. PMID: 34843982
Glioblastoma remains a cancer for which the effectiveness of treatments has shown little improvement over the last decades. For this pathology, multiple therapies combining resection, chemotherapy and radiotherapy remain the...