Reginald P Lehmann
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Explore the profile of Reginald P Lehmann including associated specialties, affiliations and a list of published articles.
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10
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47
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Recent Articles
1.
Challinor V, Johnston R, Bernhardt P, Lehmann R, Krenske E, De Voss J
Chem Sci
. 2017 Oct;
6(10):5740-5745.
PMID: 29081941
A series of novel sesterterpenes () have been isolated from the roots of and structurally characterized by MS, NMR, and X-ray crystallography in conjunction with computational modeling. Their structures provide...
2.
Challinor V, Chap S, Lehmann R, Bernhardt P, De Voss J
J Nat Prod
. 2013 Mar;
76(4):485-8.
PMID: 23514637
We report the isolation and structure elucidation of a new cheilanthane sesterterpene from the roots of Aletris farinosa that possesses an unusual malonate half-ester functional group. The structure of 1...
3.
Challinor V, Stuthe J, Parsons P, Lambert L, Lehmann R, Kitching W, et al.
J Nat Prod
. 2012 Aug;
75(8):1469-79.
PMID: 22880631
Phytochemical investigation of Chamaelirium luteum ("false unicorn") resulted in the isolation of 15 steroidal glycosides. Twelve of these (1, 2, 4-9, 11-13, and 15) are apparently unique to this species,...
4.
Challinor V, Parsons P, Chap S, White E, Blanchfield J, Lehmann R, et al.
Steroids
. 2012 Jan;
77(5):504-11.
PMID: 22285850
Phytochemical characterization of a commercial herb sample supplied as Smilax ornata Lem. (sarsaparilla) led to the isolation of five steroidal saponins, including two new furostanol saponins sarsaparilloside B (1) and...
5.
Challinor V, Hayes P, Bernhardt P, Kitching W, Lehmann R, De Voss J
J Org Chem
. 2011 Jul;
76(17):7275-80.
PMID: 21793522
The absolute stereochemistry of the steroidal saponins bethosides B and C was previously assigned as (22R,25R) on the basis of work that employed Horeau's method. Our studies of helosides A...
6.
Challinor V, Stuthe J, Bernhardt P, Lehmann R, Kitching W, De Voss J
J Nat Prod
. 2011 Jun;
74(7):1557-60.
PMID: 21692443
Investigation of Chamaelirium luteum roots led to the isolation of two new steroidal saponins, helosides A and B, that contain a previously unreported aglycone, helogenin. Their structures and absolute configuration...
7.
Matovic N, Stuthe J, Challinor V, Bernhardt P, Lehmann R, Kitching W, et al.
Chemistry
. 2011 May;
17(27):7578-91.
PMID: 21598325
Chamaelirium luteum is used in traditional medicine systems and commercial botanical dietary supplements for the treatment of female reproductive health problems. Despite the wide use of this herb, only very...
8.
Matovic N, Hayes P, Penman K, Lehmann R, De Voss J
J Org Chem
. 2011 Apr;
76(11):4467-81.
PMID: 21500842
The synthesis of 20 alkyl amides, including 15 naturally occurring polyunsaturated alkyl amides previously identified from Echinacea spp. (1-13 and 62) or from Achilla sp. (55) and five previously unknown...
9.
Abdul M, Jiang X, Williams K, Day R, Roufogalis B, Liauw W, et al.
Br J Clin Pharmacol
. 2010 Jun;
69(5):508-15.
PMID: 20573086
Aims: This study investigated the pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects. Methods: This was an open-label, randomized, three-treatment, cross-over, clinical trial in healthy...
10.
Penman K, Halstead C, Matthias A, De Voss J, Stuthe J, Bone K, et al.
J Agric Food Chem
. 2006 Sep;
54(19):7378-82.
PMID: 16968108
Vaccinium myrtillus or bilberry fruit is a commonly used herbal product. The usual method of determining the anthocyanin content is a single-wavelength spectrophotometric assay. Using this method, anthocyanin levels of...