Structure and Absolute Configuration of Helosides A and B, New Saponins from Chamaelirium Luteum

Overview

Journal J Nat Prod

Date 2011 Jun 23

PMID 21692443

Citations 3

Authors

Victoria L Challinor

Julia M U Stuthe

Paul V Bernhardt

Reginald P Lehmann

William Kitching

James J De Voss

Affiliations

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Abstract

Investigation of Chamaelirium luteum roots led to the isolation of two new steroidal saponins, helosides A and B, that contain a previously unreported aglycone, helogenin. Their structures and absolute configuration were elucidated through MS-MS, NMR, chemical degradation, and X-ray crystallography.

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