James J De Voss
Overview
Explore the profile of James J De Voss including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
117
Citations
858
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kundral S, Beamish H, Giang P, Salisbury L, Nouwens A, Khare S, et al.
Microb Biotechnol
. 2025 Mar;
18(3):e70125.
PMID: 40056075
Cytochromes P450 (P450s) are exceptional biocatalysts that enable the selective oxidation of unactivated C-H bonds using molecular oxygen. Typically, auxiliary redox partner proteins deliver electrons from NAD(P)H to the P450,...
2.
Lee J, Coleman T, McLean M, Podgorski M, Hayball E, Stone I, et al.
ACS Catal
. 2025 Feb;
14(11):8958-8971.
PMID: 39911918
The heme enzymes of the cytochrome P450 superfamily (CYPs) catalyze oxidation reactions with a high level of selectivity. Here, the CYP199A4 enzyme from the bacterium HaA2 is used to catalyze...
3.
Akter J, Lee J, Whelan F, De Voss J, Bell S, Bell S
Chembiochem
. 2024 Dec;
26(5):e202400880.
PMID: 39714419
The heme enzymes of the cytochrome P450 superfamily (CYPs) catalyse the selective hydroxylation of unactivated C-H bonds in organic molecules. There is great interest in applying these enzymes as biocatalysts...
4.
Padva L, Gullick J, Coe L, Coe L, Hansen M, Hansen M, et al.
Chembiochem
. 2024 Dec;
e202400916.
PMID: 39714378
The biarylitides are a recently discovered class of RiPP natural products that are fascinating both from the small size of the core peptides as well as the diversity of peptide...
5.
Zhao Y, Gullick J, Hansen M, Coe L, Treisman M, Schittenhelm R, et al.
Chem Commun (Camb)
. 2024 Nov;
60(94):13951-13954.
PMID: 39512132
The biarylitide crosslinking enzyme P450 can perform crosslinking between -F-Tyr-3 and His-5 residues within peptide substrates with concomitant and specific loss of fluorine. Our investigations suggest that a small intrinsic...
6.
Chhabra M, Shanthamurthy C, Kumar N, Mardhekar S, Vishweshwara S, Wimmer N, et al.
J Med Chem
. 2024 Jul;
67(14):11885-11916.
PMID: 38995734
Herein, we report the synthesis and biological evaluation of a novel series of heparinoid amphiphiles as inhibitors of heparanase and SARS-CoV-2. By employing a tailor-made synthetic strategy, a library of...
7.
Coe L, Zhao Y, Padva L, Keto A, Schittenhelm R, Tailhades J, et al.
Chemistry
. 2024 May;
30(38):e202400988.
PMID: 38712638
The structure of the sidechain crosslinked Tyr-Leu-Trp peptide produced by the biarylitide crosslinking cytochrome P450 from Micromonospora sp. MW-13 has been reanalysed by a series of NMR, computational and isotope...
8.
Treisman M, Coe L, Zhao Y, Sasi V, Gullick J, Hansen M, et al.
Org Lett
. 2024 Feb;
26(9):1828-1833.
PMID: 38417822
Cytochrome-P450-mediated cross-linking of ribosomally encoded peptides (RiPPs) is rapidly expanding and displays great potential for biocatalysis. Here, we demonstrate that active site engineering of the biarylitide cross-linking enzyme P450 enables...
9.
Churchman L, Beckett J, Tan L, Woods K, Doherty D, Ghith A, et al.
J Steroid Biochem Mol Biol
. 2024 Feb;
239:106479.
PMID: 38346478
Oxidised derivatives of cholesterol have been shown to inhibit the growth of Mycobacterium tuberculosis (Mtb). The bacteriostatic activity of these compounds has been attributed to their inhibition of CYP125A1 and...
10.
Giang P, Churchman L, Buczynski J, Bell S, Stok J, De Voss J
Arch Biochem Biophys
. 2023 Dec;
752:109852.
PMID: 38072297
Rhodococcus globerulus (R. globerulus) was isolated from the soil beneath a Eucalypt tree. Metabolic growth studies revealed that R. globerulus was capable of living on certain monoterpenes, including 1,8-cineole and...