Rebecca Shoemaker
Overview
Explore the profile of Rebecca Shoemaker including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
1870
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Recent Articles
1.
Varco-Merth B, Chaunzwa M, Duell D, Marenco A, Goodwin W, Dannay R, et al.
PLoS Pathog
. 2024 Aug;
20(8):e1012496.
PMID: 39173097
Persistence of the rebound-competent viral reservoir (RCVR) within the CD4+ T cell compartment of people living with HIV remains a major barrier to HIV cure. Here, we determined the effects...
2.
Keele B, Okoye A, Fennessey C, Varco-Merth B, Immonen T, Kose E, et al.
PLoS Pathog
. 2024 Apr;
20(4):e1012135.
PMID: 38593120
The rebound competent viral reservoir (RCVR)-virus that persists during antiretroviral treatment (ART) and can reignite systemic infection when treatment is stopped-is the primary barrier to eradicating HIV. We used time...
3.
Hansen S, Hancock M, Malouli D, Marshall E, Hughes C, Randall K, et al.
Sci Immunol
. 2022 Jun;
7(72):eabn9301.
PMID: 35714200
The strain 68-1 rhesus cytomegalovirus (RhCMV)-based vaccine for simian immunodeficiency virus (SIV) can stringently protect rhesus macaques (RMs) from SIV challenge by arresting viral replication early in primary infection. This...
4.
Barrenas F, Hansen S, Law L, Driscoll C, Green R, Smith E, et al.
PLoS Pathog
. 2021 Jul;
17(7):e1009278.
PMID: 34228762
Simian immunodeficiency virus (SIV) challenge of rhesus macaques (RMs) vaccinated with strain 68-1 Rhesus Cytomegalovirus (RhCMV) vectors expressing SIV proteins (RhCMV/SIV) results in a binary outcome: stringent control and subsequent...
5.
Verweij M, Hansen S, Iyer R, John N, Malouli D, Morrow D, et al.
Science
. 2021 Mar;
372(6541).
PMID: 33766941
Strain 68-1 rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens elicit CD8 T cells recognizing epitopes presented by major histocompatibility complex II (MHC-II) and MHC-E but not MHC-Ia....
6.
Malouli D, Hansen S, Hancock M, Hughes C, Ford J, Gilbride R, et al.
Sci Immunol
. 2021 Mar;
6(57).
PMID: 33766849
Simian immunodeficiency virus (SIV) insert-expressing, 68-1 rhesus cytomegalovirus (RhCMV/SIV) vectors elicit major histocompatibility complex E (MHC-E)- and MHC-II-restricted, SIV-specific CD8 T cell responses, but the basis of these unconventional responses...
7.
Swanstrom A, Immonen T, Oswald K, Pyle C, Thomas J, Bosche W, et al.
J Clin Invest
. 2021 Jan;
131(6).
PMID: 33465055
The effectiveness of virus-specific strategies, including administered HIV-specific mAbs, to target cells that persistently harbor latent, rebound-competent HIV genomes during combination antiretroviral therapy (cART) has been limited by inefficient induction...
8.
Hansen S, Marshall E, Malouli D, Ventura A, Hughes C, Ainslie E, et al.
Sci Transl Med
. 2019 Jul;
11(501).
PMID: 31316007
Previous studies have established that strain 68-1-derived rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) proteins (RhCMV/SIV) are able to elicit and maintain cellular immune responses that provide protection...
9.
Okoye A, Hansen S, Vaidya M, Fukazawa Y, Park H, Duell D, et al.
Nat Med
. 2018 Aug;
24(9):1430-1440.
PMID: 30082858
Prophylactic vaccination of rhesus macaques with rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens (RhCMV/SIV) elicits immune responses that stringently control highly pathogenic SIV infection, with subsequent apparent...
10.
Swanstrom A, Gorelick R, Wu G, Howell B, Vijayagopalan A, Shoemaker R, et al.
AIDS Res Hum Retroviruses
. 2018 Jun;
34(11):993-1001.
PMID: 29869527
Although effective for suppressing viral replication, combination antiretroviral treatment (cART) does not represent definitive therapy for HIV infection due to persistence of replication-competent viral reservoirs. The advent of effective cART...