Ray Jupp
Overview
Explore the profile of Ray Jupp including associated specialties, affiliations and a list of published articles.
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11
Citations
1648
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Recent Articles
1.
Thomas B, Eldridge S, Nosrati B, Alvarez M, Thorup A, Nalesso G, et al.
J Extracell Vesicles
. 2021 May;
10(7):e12088.
PMID: 34025953
Cartilage defects repair poorly. Recent genetic studies suggest that WNT3a may contribute to cartilage regeneration, however the dense, avascular cartilage extracellular matrix limits its penetration and signalling to chondrocytes. Extracellular...
2.
Mahuron K, Moreau J, Glasgow J, Boda D, Pauli M, Gouirand V, et al.
J Exp Med
. 2020 Jun;
217(9).
PMID: 32539073
Tumor-infiltrating CD8+ T cells mediate antitumor immune responses. However, the mechanisms by which T cells remain poised to kill cancer cells despite expressing high levels of inhibitory receptors are unknown....
3.
Song X, Sun X, Oh S, Wu M, Zhang Y, Zheng W, et al.
Nature
. 2019 Dec;
577(7790):410-415.
PMID: 31875848
The metabolic pathways encoded by the human gut microbiome constantly interact with host gene products through numerous bioactive molecules. Primary bile acids (BAs) are synthesized within hepatocytes and released into...
4.
Geva-Zatorsky N, Sefik E, Kua L, Pasman L, Tan T, Ortiz-Lopez A, et al.
Cell
. 2017 Feb;
168(5):928-943.e11.
PMID: 28215708
Within the human gut reside diverse microbes coexisting with the host in a mutually advantageous relationship. Evidence has revealed the pivotal role of the gut microbiota in shaping the immune...
5.
Tan T, Sefik E, Geva-Zatorsky N, Kua L, Naskar D, Teng F, et al.
Proc Natl Acad Sci U S A
. 2016 Dec;
113(50):E8141-E8150.
PMID: 27911839
Th17 cells accrue in the intestine in response to particular microbes. In rodents, segmented filamentous bacteria (SFB) induce intestinal Th17 cells, but analogously functioning microbes in humans remain undefined. Here,...
6.
Sefik E, Geva-Zatorsky N, Oh S, Konnikova L, Zemmour D, Manson McGuire A, et al.
Science
. 2015 Aug;
349(6251):993-7.
PMID: 26272906
T regulatory cells that express the transcription factor Foxp3 (Foxp3(+) T(regs)) promote tissue homeostasis in several settings. We now report that symbiotic members of the human gut microbiota induce a...
7.
Mazuc E, Guglielmi L, Bec N, Parez V, Hahn C, Mollevi C, et al.
PLoS One
. 2014 Aug;
9(8):e104998.
PMID: 25122211
The high specificity of antibodies for their antigen allows a fine discrimination of target conformations and post-translational modifications, making antibodies the first choice tool to interrogate the proteome. We describe...
8.
Williams A, Eynott P, Leung S, Nath P, Jupp R, De Sanctis G, et al.
Pulm Pharmacol Ther
. 2008 Dec;
22(1):27-32.
PMID: 19041950
Ambient ozone has been linked to the worsening of symptoms of patients with obstructive diseases such as chronic obstructive pulmonary disease (COPD) and asthma. We investigated the role of cathepsin...
9.
Das J, Eynott P, Jupp R, Bothwell A, Van Kaer L, Shi Y, et al.
Nat Med
. 2006 Dec;
12(12):1345-6.
PMID: 17151684
No abstract available.
10.
Daheshia M, Tian N, Connolly T, Drawid A, Wu Q, Bienvenu J, et al.
Ann N Y Acad Sci
. 2003 Jan;
975:148-59.
PMID: 12538161
Asthma is one of the foremost contributors to morbidity and mortality in industrialized countries. Our objective was to characterize the acute response to allergen and to identify potentially novel molecular...