Raphael A Zoeller
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Explore the profile of Raphael A Zoeller including associated specialties, affiliations and a list of published articles.
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15
Citations
388
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Recent Articles
1.
Shakya S, Herr R, Carlson H, Zoeller R, Albert C, Ford D
Antioxidants (Basel)
. 2022 May;
11(5).
PMID: 35624804
Neutrophils are important cellular mediators of injury and repair in diseases including ischemic heart disease, atherosclerosis, and sepsis. Myeloperoxidase-derived (MPO)-oxidants released from neutrophils are potential mediators of endothelial injury in...
2.
Honsho M, Tanaka M, Zoeller R, Fujiki Y
Front Cell Dev Biol
. 2020 Oct;
8:855.
PMID: 33042986
Plasmalogens are a subclass of ether glycerophospholipids characterized by a vinyl-ether bond at the -1 position of the glycerol backbone. Plasmalogen biosynthesis is initiated in peroxisomes. At the third step...
3.
Werner E, Keller M, Sailer S, Lackner K, Koch J, Hermann M, et al.
Proc Natl Acad Sci U S A
. 2020 Mar;
117(14):7792-7798.
PMID: 32209662
A significant fraction of the glycerophospholipids in the human body is composed of plasmalogens, particularly in the brain, cardiac, and immune cell membranes. A decline in these lipids has been...
4.
Zoeller R, Geoghegan-Barek K
Biochem Biophys Rep
. 2019 Mar;
18:100621.
PMID: 30899803
Inhibition of animal cell phospholipid biosynthesis has been proposed for anticancer and antiviral therapies. Using CHO-K1 derived cell lines, we have developed and used a cell-based high-throughput procedure to screen...
5.
Werner E, Keller M, Sailer S, Seppi D, Golderer G, Werner-Felmayer G, et al.
J Lipid Res
. 2018 Mar;
59(5):901-909.
PMID: 29540573
Plasmanylethanolamine desaturase (PEDS) (EC 1.14.99.19) introduces the 1-prime double bond into plasmalogens, one of the most abundant phospholipids in the human body. This labile membrane enzyme has not been purified...
6.
Nakahara K, Ohkuni A, Kitamura T, Abe K, Naganuma T, Ohno Y, et al.
Mol Cell
. 2012 May;
46(4):461-71.
PMID: 22633490
Sphingosine 1-phosphate (S1P) functions not only as a bioactive lipid molecule, but also as an important intermediate of the sole sphingolipid-to-glycerolipid metabolic pathway. However, the precise reactions and the enzymes...
7.
Krawczyk S, Haller J, Ferrante T, Zoeller R, Corkey B
PLoS One
. 2012 Apr;
7(4):e34904.
PMID: 22493722
In obesity, there is an increase in reactive oxygen species (ROS) within adipose tissue caused by increases in inflammation and overnutrition. Hormone sensitive lipase (HSL) is part of the canonical...
8.
Haller J, Krawczyk S, Gostilovitch L, Corkey B, Zoeller R
Biochim Biophys Acta
. 2011 Jul;
1812(11):1393-402.
PMID: 21787864
Inherited glucose-6-phosphate isomerase (GPI) deficiency is the second most frequent glycolytic erythroenzymopathy in humans. Patients present with non-spherocytic anemia of variable severity and with neuromuscular dysfunction. We previously described Chinese...
9.
Anbukumar D, Shornick L, Albert C, Steward M, Zoeller R, Neumann W, et al.
J Lipid Res
. 2009 Dec;
51(5):1085-92.
PMID: 20019386
Neutrophils are important in the host response against invading pathogens. One chemical defense mechanism employed by neutrophils involves the production of myeloperoxidase (MPO)-derived HOCl. 2-Chlorohexadecanal (2-ClHDA) is a naturally occurring...
10.
Haller J, Smith C, Liu D, Zheng H, Tornheim K, Han G, et al.
J Biol Chem
. 2009 Nov;
285(2):866-77.
PMID: 19903819
Glycerolipids are structural components for membranes and serve in energy storage. We describe here the use of a photodynamic selection technique to generate a population of Chinese hamster ovary cells...