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Ranjana K Kanchan

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Articles 12
Citations 127
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Recent Articles
1.
Maurya S, Jaramillo-Gomez J, Rehman A, Gautam S, Fatima M, Khan M, et al.
Clin Cancer Res . 2025 Jan; 31(5):921-935. PMID: 39760691
Purpose: Breast cancer brain metastasis remains a significant clinical problem. Mucins have been implicated in metastasis; however, whether they are also involved in breast cancer brain metastasis remains unknown. We...
2.
Perumal N, Gopalakrishnan P, Burkovetskaya M, Doss D, Dukkipati S, Kanchan R, et al.
Cancer Lett . 2024 Nov; 609:217349. PMID: 39581218
The nuclear factor I (NFI) family of transcription factors plays a decisive role in organ development and maturation. Their deregulation has been linked with various diseases, most notably cancer. NFIB...
3.
Abdullah K, Sharma G, Qais F, Khan I, Takkar S, Kaushal J, et al.
Int J Biol Macromol . 2024 Mar; 266(Pt 1):130912. PMID: 38513896
Patients with advanced prostate cancer (PCa) are more likely to develop bone metastases. Tumor cells thrive in the bone microenvironment, interacting with osteoblasts and osteoclasts. Given the PI3K/AKT pathway's metastatic...
4.
Kanchan R, Doss D, Khan P, Nasser M, Mahapatra S
Biochim Biophys Acta Rev Cancer . 2022 Aug; 1877(5):188783. PMID: 36028149
Targeting the anti-tumor immune response via the B7 family of immune-regulatory checkpoint proteins has revolutionized cancer treatment and resulted in punctuated responses in patients. B7-H3 has gained recent attention given...
5.
Maurya S, Khan P, Rehman A, Kanchan R, Perumal N, Mahapatra S, et al.
Semin Cancer Biol . 2021 Dec; 86(Pt 3):914-930. PMID: 34968667
Brain metastasis (BrM) is one of the major causes of death in cancer patients and is associated with an estimated 10-40 % of total cancer cases. The survival rate of...
6.
Perumal N, Kanchan R, Doss D, Bastola N, Atri P, Chirravuri-Venkata R, et al.
Acta Neuropathol Commun . 2021 Dec; 9(1):195. PMID: 34922631
Haploinsufficiency of chromosome 17p and c-Myc amplification distinguish group 3 medulloblastomas which are associated with early metastasis, rapid recurrence, and swift mortality. Tumor suppressor genes on this locus have not...
7.
Kaushal J, Bhatia R, Kanchan R, Raut P, Mallapragada S, Ly Q, et al.
Cancers (Basel) . 2021 Nov; 13(22). PMID: 34831024
The authors would like to make a correction to their published paper [...].
8.
Kaushal J, Bhatia R, Kanchan R, Raut P, Mallapragada S, Ly Q, et al.
Cancers (Basel) . 2021 Jul; 13(13). PMID: 34206370
Niclosamide (Nic), an FDA-approved anthelmintic drug, is reported to have anti-cancer efficacy and is being assessed in clinical trials for various solid tumors. Based on its ability to target multiple...
9.
Gautam S, Kanchan R, Siddiqui J, Maurya S, Rauth S, Perumal N, et al.
Cancers (Basel) . 2020 Oct; 12(10). PMID: 33019652
Brain metastasis (BrM) remains a significant cause of cancer-related mortality in epidermal growth factor receptor 2-positive (ERBB2) breast cancer (BC) patients. We proposed here that a combination treatment of irreversible...
10.
Kanchan R, Perumal N, Atri P, Chirravuri Venkata R, Thapa I, Klinkebiel D, et al.
Brain Pathol . 2020 Mar; 30(4):732-745. PMID: 32145124
Of the four primary subgroups of medulloblastoma, the most frequent cytogenetic abnormality, i17q, distinguishes Groups 3 and 4 which carry the highest mortality; haploinsufficiency of 17p13.3 is a marker for...