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Randall L Mynatt

Explore the profile of Randall L Mynatt including associated specialties, affiliations and a list of published articles. Areas
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Articles 61
Citations 3281
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Recent Articles
1.
Warfel J, Elks C, Bayless D, Vandanmagsar B, Stone A, Velasquez S, et al.
Acta Physiol (Oxf) . 2023 Jan; 238(1):e13935. PMID: 36650072
Aim: Valuable studies have tested the role of UCP1 on body temperature maintenance in mice, and we sought to knockout Ucp1 in rats (Ucp1 ) to provide insight into thermogenic...
2.
Mynatt R, Noland R, Elks C, Vandanmagsar B, Bayless D, Stone A, et al.
Metabolism . 2022 Nov; 138:155345. PMID: 36410080
No abstract available.
3.
Angelini A, Saha P, Jain A, Jung S, Mynatt R, Pi X, et al.
Cell Rep . 2021 Oct; 37(1):109767. PMID: 34610308
Cardiac metabolism is a high-oxygen-consuming process, showing a preference for long-chain fatty acid (LCFA) as the fuel source under physiological conditions. However, a metabolic switch (favoring glucose instead of LCFA)...
4.
Stone A, Noland R, Mynatt R, Velasquez S, Bayless D, Ravussin E, et al.
Biology (Basel) . 2021 Jul; 10(6). PMID: 34204316
Male mice lacking HuR in skeletal muscle (HuR) have been shown to have decreased gastrocnemius lipid oxidation and increased adiposity and insulin resistance. The same consequences have not been documented...
5.
Ali M, McMillan R, Fausnacht D, Kavanaugh J, Harvey M, Stevens J, et al.
Med Sci Sports Exerc . 2020 Dec; 53(6):1161-1169. PMID: 33315811
Purpose: Toll-like receptor 4 (TLR4) is an inflammatory receptor expressed ubiquitously in immune cells as well as skeletal muscle and other metabolic tissues. Skeletal muscle develops favorable inflammation-mediated metabolic adaptations...
6.
Collier J, Batdorf H, Martin T, Rohli K, Burk D, Lu D, et al.
Mol Metab . 2020 Dec; 44:101140. PMID: 33285301
Objective: The expression of the interleukin-1 receptor type I (IL-1R) is enriched in pancreatic islet β-cells, signifying that ligands activating this pathway are important for the health and function of...
7.
Collier J, Batdorf H, Mendoza T, Burk D, Martin T, Zhang J, et al.
Am J Physiol Endocrinol Metab . 2019 Oct; 318(1):E11-E21. PMID: 31661298
There are endocrine and immunological changes that occur during onset and progression of the overweight and obese states. The inhibitor of nuclear factor-κB kinase-ε (IKKε) was originally described as an...
8.
Mynatt R, Noland R, Elks C, Vandanmagsar B, Bayless D, Stone A, et al.
Metabolism . 2019 May; 97:40-49. PMID: 31129047
Background: Metabolic flexibility can be assessed by changes in respiratory exchange ratio (RER) following feeding. Though metabolic flexibility (difference in RER between fasted and fed state) is often impaired in...
9.
Ghosh S, Wicks S, Vandanmagsar B, Mendoza T, Bayless D, Salbaum J, et al.
J Biol Chem . 2019 May; 294(33):12313-12327. PMID: 31097541
Mitochondrial lipid overload in skeletal muscle contributes to insulin resistance, and strategies limiting this lipid pressure improve glucose homeostasis; however, comprehensive cellular adaptations that occur in response to such an...
10.
Mynatt R, Ravussin E
Cell . 2018 Dec; 175(6):1459-1460. PMID: 30500531
Most theories of meal-induced thermogenesis involve a gut-brain-brown adipose tissue axis driving sympathetic nervous system-mediated thermogenesis. Li et al. demonstrate that secretin released by the gut after a meal binds...