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Ralf Kuppers

Explore the profile of Ralf Kuppers including associated specialties, affiliations and a list of published articles. Areas
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Articles 196
Citations 6382
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Recent Articles
1.
Glaser S, Fischer A, Martinez-Manjon J, Lopez C, Kretzmer H, Burkhardt B, et al.
Leukemia . 2025 Mar; PMID: 40065077
No abstract available.
2.
Dampmann M, Kibler A, von Tresckow J, Reinhardt H, Kuppers R, Budeus B
Leuk Lymphoma . 2024 Dec; :1-9. PMID: 39689719
Dual productive B-cell receptor (BCR) rearrangements have been repeatedly reported for chronic lymphocytic leukemia (CLL), but the standard population-based PCR analyses cannot distinguish whether these are bi-clonal CLL, or a...
3.
Kuppers R
Trends Mol Med . 2024 Oct; PMID: 39443214
Hodgkin lymphoma (HL) has been and still is the most enigmatic lymphoid malignancy in humans. Since the first molecular analysis of isolated Hodgkin and Reed-Sternberg (HRS) tumor cells of classic...
4.
Kuppers R, Hansmann M
Methods Mol Biol . 2024 Oct; 2865:61-76. PMID: 39424720
Normal and malignant B cells carry rearranged immunoglobulin (Ig) variable region genes, which due to their practically limitless diversity represent ideal clonal markers for these cells. We describe here an...
5.
Weniger M, Seifert M, Kuppers R
Methods Mol Biol . 2024 Oct; 2865:1-30. PMID: 39424718
Immunoglobulin (IG) gene remodeling by V(D)J recombination plays a central role in the generation of normal B cells, and somatic hypermutation and class switching of IG genes are key processes...
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Kuppers R
Blood . 2024 Aug; 144(5):469-471. PMID: 39088230
No abstract available.
8.
Kuppers R
Nat Cell Biol . 2024 Feb; 26(3):323-324. PMID: 38379050
No abstract available.
9.
Massoni-Badosa R, Aguilar-Fernandez S, Nieto J, Soler-Vila P, Elosua-Bayes M, Marchese D, et al.
Immunity . 2024 Feb; 57(2):379-399.e18. PMID: 38301653
Palatine tonsils are secondary lymphoid organs (SLOs) representing the first line of immunological defense against inhaled or ingested pathogens. We generated an atlas of the human tonsil composed of >556,000...
10.
Budeus B, Kibler A, Kuppers R
Front Immunol . 2023 Dec; 14:1308378. PMID: 38143767
A hallmark of T cell dependent (TD) humoral immune responses is the generation of long-lived memory B cells. The generation of these cells occurs primarily in the germinal center (GC)...