Rajkumar Noubade
Overview
Explore the profile of Rajkumar Noubade including associated specialties, affiliations and a list of published articles.
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31
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1666
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Recent Articles
21.
Noubade R, Krementsov D, Del Rio R, Thornton T, Nagaleekar V, Saligrama N, et al.
Blood
. 2011 Jul;
118(12):3290-300.
PMID: 21791428
Although several transcription factors have been shown to be critical for the induction and maintenance of IL-17 expression by CD4 Th cells, less is known about the role of nontranscriptional...
22.
Lu C, Diehl S, Noubade R, Ledoux J, Nelson M, Spach K, et al.
Proc Natl Acad Sci U S A
. 2010 Oct;
107(44):18967-72.
PMID: 20956310
Disruption of the blood-brain barrier (BBB) underlies the development of experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis. Environmental factors, such as Bordetella pertussis, are thought to sensitize central endothelium to...
23.
Spach K, Noubade R, McElvany B, Hickey W, Blankenhorn E, Teuscher C
J Immunol
. 2009 Jun;
182(12):7776-83.
PMID: 19494301
Genes controlling immunopathologic diseases of differing etiopathology may also influence susceptibility to autoimmune disease. B10.D1-H2(q)/SgJ mice with a 2538 G-->A missense mutation in the tyrosine kinase-2 gene (Tyk2) are susceptible...
24.
Spach K, Blake M, Bunn J, McElvany B, Noubade R, Blankenhorn E, et al.
J Immunol
. 2009 Feb;
182(4):1789-93.
PMID: 19201829
Multiple sclerosis is a sexually dimorphic, demyelinating disease of the CNS, and experimental allergic encephalomyelitis (EAE) is its principal autoimmune model. Young male SJL/J mice are relatively resistant to EAE...
25.
Dienz O, Eaton S, Bond J, Neveu W, Moquin D, Noubade R, et al.
J Exp Med
. 2009 Jan;
206(1):69-78.
PMID: 19139170
Interleukin (IL) 6 is a proinflammtory cytokine produced by antigen-presenting cells and nonhematopoietic cells in response to external stimuli. It was initially identified as a B cell growth factor and...
26.
Noubade R, Del Rio R, McElvany B, Zachary J, Millward J, Wagner D, et al.
Am J Pathol
. 2008 Aug;
173(3):892-900.
PMID: 18688020
Weibel-Palade bodies within endothelial cells are secretory granules known to release von Willebrand Factor (VWF), P-selectin, chemokines, and other stored molecules following histamine exposure. Mice with a disrupted VWF gene...
27.
Lu C, Pelech S, Zhang H, Bond J, Spach K, Noubade R, et al.
J Neurosci Res
. 2008 May;
86(12):2624-40.
PMID: 18500752
Pertussis toxin (PTX) is an ancillary adjuvant used to elicit experimental allergic encephalomyelitis (EAE), the principal autoimmune model of multiple sclerosis. One mechanism whereby PTX potentiates EAE is to increase...
28.
Noubade R, Saligrama N, Spach K, Del Rio R, Blankenhorn E, Kantidakis T, et al.
J Immunol
. 2008 May;
180(11):7471-9.
PMID: 18490747
Structural polymorphisms (L263P, M313V, and S331P) in the third intracellular loop of the murine histamine receptor H(1) (H(1)R) are candidates for Bphs, a shared autoimmune disease locus in experimental allergic...
29.
Noubade R, Milligan G, Zachary J, Blankenhorn E, Del Rio R, Rincon M, et al.
J Clin Invest
. 2007 Oct;
117(11):3507-18.
PMID: 17965772
Histamine receptor H1 (H1R) is a susceptibility gene in both experimental autoimmune encephalomyelitis (EAE) and experimental autoimmune orchitis (EAO), 2 classical T cell-mediated models of organ-specific autoimmune disease. Here we...
30.
Teuscher C, Subramanian M, Noubade R, Gao J, Offner H, Zachary J, et al.
Proc Natl Acad Sci U S A
. 2007 Jun;
104(24):10146-51.
PMID: 17548817
Histamine (HA), a biogenic amine with a broad spectrum of activities in both physiological and pathological settings, plays a key regulatory role in experimental allergic encephalomyelitis, the autoimmune model of...