Rajkumar Noubade
Overview
Explore the profile of Rajkumar Noubade including associated specialties, affiliations and a list of published articles.
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31
Citations
1666
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Recent Articles
11.
Diehl S, McElvany B, Noubade R, Seeberger N, Harding B, Spach K, et al.
Infect Immun
. 2014 Jan;
82(2):773-82.
PMID: 24478091
Pertussis toxin (PTX) is an AB5-type exotoxin produced by the bacterium Bordetella pertussis, the causative agent of whooping cough. In vivo intoxication with PTX elicits a variety of immunologic and...
12.
Krementsov D, Noubade R, Dragon J, Otsu K, Rincon M, Teuscher C
Ann Neurol
. 2013 Sep;
75(1):50-66.
PMID: 24027119
Objective: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS), characterized by a global increasing incidence driven by relapsing-remitting disease in females. Investigators have...
13.
Krementsov D, Wall E, Martin R, Subramanian M, Noubade R, Del Rio R, et al.
PLoS One
. 2013 Jul;
8(7):e62743.
PMID: 23894272
Histamine H(3) receptor (Hrh3/H(3)R) is primarily expressed by neurons in the central nervous system (CNS) where it functions as a presynaptic inhibitory autoreceptor and heteroreceptor. Previously, we identified an H(3)R-mediated...
14.
Saligrama N, Case L, Del Rio R, Noubade R, Teuscher C
J Immunol
. 2013 Jun;
191(2):614-22.
PMID: 23772030
Histamine (HA) is a key regulator of experimental allergic encephalomyelitis (EAE), the autoimmune model of multiple sclerosis. HA exerts its effects through four known G-protein-coupled receptors: H1, H2, H3, and...
15.
Saligrama N, Noubade R, Case L, Poynter M, Teuscher C
Cell Immunol
. 2012 Nov;
278(1-2):27-34.
PMID: 23121973
The histamine H(1) receptor (Hrh1/H(1)R) was identified as an autoimmune disease gene in experimental allergic encephalomyelitis (EAE), the principal autoimmune model of multiple sclerosis (MS). Previously, we showed that selective...
16.
Dey A, Seshasayee D, Noubade R, French D, Liu J, Chaurushiya M, et al.
Science
. 2012 Aug;
337(6101):1541-6.
PMID: 22878500
De-ubiquitinating enzyme BAP1 is mutated in a hereditary cancer syndrome with increased risk of mesothelioma and uveal melanoma. Somatic BAP1 mutations occur in various malignancies. We show that mouse Bap1...
17.
Saligrama N, Noubade R, Case L, Del Rio R, Teuscher C
Eur J Immunol
. 2012 Jun;
42(6):1536-46.
PMID: 22678907
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system in which histamine (HA) and its receptors have been implicated in disease pathogenesis. HA exerts its...
18.
Del Rio R, Noubade R, Saligrama N, Wall E, Krementsov D, Poynter M, et al.
J Immunol
. 2011 Dec;
188(2):541-7.
PMID: 22147765
Histamine is a biogenic amine that mediates multiple physiological processes, including immunomodulatory effects in allergic and inflammatory reactions, and also plays a key regulatory role in experimental allergic encephalomyelitis, the...
19.
Case L, Moussawi M, Roberts B, Noubade R, Huber S, Teuscher C
Cell Immunol
. 2011 Nov;
272(2):269-74.
PMID: 22078271
Susceptibility to autoimmune myocarditis has been associated with histamine release by mast cells during the innate immune response to coxsackievirus B3 (CVB3) infection. To investigate the contribution of histamine H(1)...
20.
Rutz S, Noubade R, Eidenschenk C, Ota N, Zeng W, Zheng Y, et al.
Nat Immunol
. 2011 Oct;
12(12):1238-45.
PMID: 22001828
Interleukin 22 (IL-22), which is produced by cells of the T(H)17 subset of helper T cells and other leukocytes, not only enhances proinflammatory innate defense mechanisms in epithelial cells but...