Rajib K Paul
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Explore the profile of Rajib K Paul including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
388
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Recent Articles
1.
Wnorowski A, Such J, Paul R, Wersto R, Indig F, Jozwiak K, et al.
Cell Signal
. 2017 May;
36:176-188.
PMID: 28495590
Activation of β-adrenergic receptor (βAR) and deorphanized GPR55 has been shown to modulate cancer growth in diverse tumor types in vitro and in xenograft models in vivo. (R,R')-4'-methoxy-1-naphthylfenoterol [(R,R')-MNF] is...
2.
Garcia-Matas S, Paul R, Molina-Martinez P, Palacios H, Gutierrez V, Corpas R, et al.
Aging Cell
. 2015 Feb;
14(3):334-44.
PMID: 25711920
Astrocytes are key cells in brain aging, helping neurons to undertake healthy aging or otherwise letting them enter into a spiral of neurodegeneration. We aimed to characterize astrocytes cultured from...
3.
Wnorowski A, Sadowska M, Paul R, Singh N, Boguszewska-Czubara A, Jimenez L, et al.
Cell Signal
. 2015 Feb;
27(5):997-1007.
PMID: 25703025
(R,R')-4'-methoxy-1-naphthylfenoterol [(R,R')-MNF] is a highly-selective β2 adrenergic receptor (β2-AR) agonist. Incubation of a panel of human-derived melanoma cell lines with (R,R')-MNF resulted in a dose- and time-dependent inhibition of motility...
4.
Bernier M, Paul R, Dossou K, Wnorowski A, Ramamoorthy A, Paris A, et al.
Pharmacol Res Perspect
. 2014 Dec;
1(2):e00010.
PMID: 25505565
(R,R')-4-methoxy-1-naphthylfenoterol (MNF) inhibits cancer cell proliferation in vitro through cell-type specific modulation of β2-adrenergic receptor and/or cannabinoid receptor function. Here, we report an investigation into antitumor activity of MNF in...
5.
Paul R, Singh N, Khadeer M, Moaddel R, Sanghvi M, Green C, et al.
Anesthesiology
. 2014 Jun;
121(1):149-59.
PMID: 24936922
Background: Subanesthetic doses of (R,S)-ketamine are used in the treatment of neuropathic pain and depression. In the rat, the antidepressant effects of (R,S)-ketamine are associated with increased activity and function...
6.
Woo A, Jozwiak K, Toll L, Tanga M, Kozocas J, Jimenez L, et al.
J Biol Chem
. 2014 May;
289(28):19351-63.
PMID: 24831005
Interaction of a given G protein-coupled receptor to multiple different G proteins is a widespread phenomenon. For instance, β2-adrenoceptor (β2-AR) couples dually to Gs and Gi proteins. Previous studies have...
7.
Paul R, Wnorowski A, Gonzalez-Mariscal I, Nayak S, Pajak K, Moaddel R, et al.
Biochem Pharmacol
. 2013 Dec;
87(4):547-61.
PMID: 24355564
(R,R')-4'-Methoxy-1-naphthylfenoterol (MNF) promotes growth inhibition and apoptosis of human HepG2 hepatocarcinoma cells via cannabinoid receptor (CBR) activation. The synthetic CB1R inverse agonist, AM251, has been shown to block the anti-mitogenic...
8.
Singh N, Paul R, Ramamoorthy A, Torjman M, Moaddel R, Bernier M, et al.
Cell Signal
. 2013 Sep;
25(12):2634-45.
PMID: 24012499
Western blot analysis demonstrated that PC-12 cells express monomeric and dimeric forms of serine racemase (m-SR, d-SR) and that 1321N1 cells express m-SR. Quantitative RT-PCR and functional studies demonstrated that...
9.
Singh N, Paul R, Torjman M, Wainer I
Neurosci Lett
. 2013 Jan;
535:90-4.
PMID: 23274708
The effects of gabapentin (GBP) and (S)-pregabalin (PGB) on the intracellular concentrations of d-serine and the expression of serine racemase (SR) in PC-12 cells were determined. Intracellular d-serine concentrations were...
10.
Paul R, Ramamoorthy A, Scheers J, Wersto R, Toll L, Jimenez L, et al.
J Pharmacol Exp Ther
. 2012 Jul;
343(1):157-66.
PMID: 22776956
Inhibition of cell proliferation by fenoterol and fenoterol derivatives in 1321N1 astrocytoma cells is consistent with β(2)-adrenergic receptor (β(2)-AR) stimulation. However, the events that result in fenoterol-mediated control of cell...