Rajeshwari Subray Bhat
Overview
Explore the profile of Rajeshwari Subray Bhat including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
4
Citations
73
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ekins S, Godbole A, Keri G, Orfi L, Pato J, Bhat R, et al.
Tuberculosis (Edinb)
. 2017 Feb;
103:52-60.
PMID: 28237034
There is a shortage of compounds that are directed towards new targets apart from those targeted by the FDA approved drugs used against Mycobacterium tuberculosis. Topoisomerase I (Mttopo I) is...
2.
Godbole A, Ahmed W, Bhat R, Bradley E, Ekins S, Nagaraja V
Antimicrob Agents Chemother
. 2014 Dec;
59(3):1549-57.
PMID: 25534741
We describe inhibition of Mycobacterium tuberculosis topoisomerase I (MttopoI), an essential mycobacterial enzyme, by two related compounds, imipramine and norclomipramine, of which imipramine is clinically used as an antidepressant. These...
3.
Godbole A, Ahmed W, Bhat R, Bradley E, Ekins S, Nagaraja V
Biochem Biophys Res Commun
. 2014 Mar;
446(4):916-20.
PMID: 24642256
m-AMSA, an established inhibitor of eukaryotic type II topoisomerases, exerts its cidal effect by binding to the enzyme-DNA complex thus inhibiting the DNA religation step. The molecule and its analogues...
4.
Leelaram M, Bhat A, Godbole A, Bhat R, Manjunath R, Nagaraja V
FASEB J
. 2013 Apr;
27(8):3030-8.
PMID: 23612788
Bacterial DNA topoisomerase I (topoI) catalyzes relaxation of negatively supercoiled DNA. The enzyme alters DNA topology through protein-operated DNA gate, switching between open and closed conformations during its reaction. We...