Rajendran Sanalkumar
Overview
Explore the profile of Rajendran Sanalkumar including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
26
Citations
714
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0
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Recent Articles
11.
DeVilbiss A, Sanalkumar R, Hall B, Katsumura K, Fraga de Andrade I, Bresnick E
Mol Cell Biol
. 2015 Apr;
35(12):2073-87.
PMID: 25855754
Erythropoiesis, in which committed progenitor cells generate millions of erythrocytes daily, involves dramatic changes in the chromatin structure and transcriptome of erythroblasts, prior to their enucleation. While the involvement of...
12.
DeVilbiss A, Sanalkumar R, Johnson K, Keles S, Bresnick E
Exp Hematol
. 2014 May;
42(8):618-29.
PMID: 24816274
Hematopoiesis is an exquisitely regulated process in which stem cells in the developing embryo and the adult generate progenitor cells that give rise to all blood lineages. Master regulatory transcription...
13.
Hewitt K, Sanalkumar R, Johnson K, Keles S, Bresnick E
Curr Opin Hematol
. 2014 Apr;
21(3):155-64.
PMID: 24722192
Purpose Of Review: Erythropoiesis, in which hematopoietic stem cells (HSCs) generate lineage-committed progenitors that mature into erythrocytes, is regulated by numerous chromatin modifying and remodeling proteins. We will focus on...
14.
Sanalkumar R, Johnson K, Gao X, Boyer M, Chang Y, Hewitt K, et al.
Proc Natl Acad Sci U S A
. 2014 Mar;
111(12):E1091-100.
PMID: 24616499
The unremitting demand to replenish differentiated cells in tissues requires efficient mechanisms to generate and regulate stem and progenitor cells. Although master regulatory transcription factors, including GATA binding protein-2 (GATA-2),...
15.
Zeng X, Sanalkumar R, Bresnick E, Li H, Chang Q, Keles S
Genome Biol
. 2013 Jul;
14(4):R38.
PMID: 23844871
The ChIP-seq technique enables genome-wide mapping of in vivo protein-DNA interactions and chromatin states. Current analytical approaches for ChIP-seq analysis are largely geared towards single-sample investigations, and have limited applicability...
16.
Hsu A, Johnson K, Falcone E, Sanalkumar R, Sanchez L, Hickstein D, et al.
Blood
. 2013 Mar;
121(19):3830-7, S1-7.
PMID: 23502222
Previous reports of GATA2 mutations have focused on the coding region of the gene or full gene deletions. We recently identified 2 patients with novel insertion/deletion mutations predicted to result...
17.
Kang Y, Sanalkumar R, OGeen H, Linnemann A, Chang C, Bouhassira E, et al.
Mol Cell Biol
. 2011 Oct;
32(1):226-39.
PMID: 22025678
Developmental and homeostatic remodeling of cellular organelles is mediated by a complex process termed autophagy. The cohort of proteins that constitute the autophagy machinery functions in a multistep biochemical pathway....
18.
Chung D, Kuan P, Li B, Sanalkumar R, Liang K, Bresnick E, et al.
PLoS Comput Biol
. 2011 Jul;
7(7):e1002111.
PMID: 21779159
Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) is rapidly replacing chromatin immunoprecipitation combined with genome-wide tiling array analysis (ChIP-chip) as the preferred approach for mapping transcription-factor binding sites and chromatin...
19.
Indulekha C, Divya T, Divya M, Sanalkumar R, Rasheed V, Dhanesh S, et al.
Cell Mol Life Sci
. 2011 Jul;
69(4):611-27.
PMID: 21744064
Tlx3 (HOX11L2) is regarded as one of the selector genes in excitatory versus inhibitory fate specification of neurons in distinct regions of the nervous system. Expression of Tlx3 in a...
20.
Fujiwara T, Lee H, Sanalkumar R, Bresnick E
Proc Natl Acad Sci U S A
. 2010 Nov;
107(47):20429-34.
PMID: 21059912
Developmental control mechanisms often use multimeric complexes containing transcription factors, coregulators, and additional non-DNA binding components. It is challenging to ascertain how such components contribute to complex function at endogenous...