Rajan Lamichhane
Overview
Explore the profile of Rajan Lamichhane including associated specialties, affiliations and a list of published articles.
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Articles
50
Citations
578
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Recent Articles
1.
Schuck R, Ward A, Sahoo A, Rybak J, Pyron R, Trybala T, et al.
Commun Biol
. 2025 Mar;
8(1):411.
PMID: 40069393
The receptor tyrosine kinase EphA2 drives cancer malignancy by facilitating metastasis. EphA2 can be found in different self-assembly states: as a monomer, dimer, and oligomer. However, we have a poor...
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Sundaram S, Lamichhane R, Cecchetti A, Murughiyan U, Sundaram U
Cancers (Basel)
. 2024 Oct;
16(19).
PMID: 39409969
: Dysfunctions of metabolic syndrome (MetS) have been identified as a significant risk factor for colorectal cancer (CRC). However, current colon cancer guidelines do not classify patients with MetS as...
5.
El-Dallal M, Lamichhane R, Sherif A, Frandah W
Am J Gastroenterol
. 2024 Sep;
119(12):2545.
PMID: 39324987
No abstract available.
6.
Schuck R, Ward A, Sahoo A, Rybak J, Pyron R, Trybala T, et al.
bioRxiv
. 2024 Jun;
PMID: 38915729
The receptor tyrosine kinase EphA2 drives cancer malignancy by facilitating metastasis. EphA2 can be found in different self-assembly states: as a monomer, dimer, and oligomer. However, our understanding remains limited...
7.
Agyemang E, Gonneville A, Tiruvadi-Krishnan S, Lamichhane R
Methods
. 2024 Apr;
226:35-48.
PMID: 38604413
G protein-coupled receptors (GPCRs) are membrane proteins that transmit specific external stimuli into cells by changing their conformation. This conformational change allows them to couple and activate G-proteins to initiate...
8.
Wei S, Pour N, Tiruvadi-Krishnan S, Ray A, Thakur N, Eddy M, et al.
Commun Biol
. 2023 Nov;
6(1):1218.
PMID: 38036689
Mutations that constitutively activate G protein-coupled receptors (GPCRs), known as constitutively activating mutations (CAMs), modify cell signaling and interfere with drugs, resulting in diseases with limited treatment options. We utilize...
9.
Sundaram V, Lamichhane R, Cecchetti A, Arthur S, Murughiyan U
Life (Basel)
. 2023 Sep;
13(9).
PMID: 37763336
Introduction: Metabolic syndrome amplifies the risk of gestational diabetes, preeclampsia, and preterm labor in pregnant women. Similarly, women with substance use disorder have worsened obstetric and birth outcomes. Despite these...
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Liu T, Khanal S, Hertslet G, Lamichhane R
J Biol Chem
. 2023 Aug;
299(9):105160.
PMID: 37586587
Dynamic information is vital to understanding the activation mechanism of G protein-coupled receptors (GPCRs). Despite the availability of high-resolution structures of different conformational states, the dynamics of those states at...