Rainer Blasczyk
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Explore the profile of Rainer Blasczyk including associated specialties, affiliations and a list of published articles.
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204
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2744
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Recent Articles
1.
Dragon A, Bonifacius A, Lienenklaus S, Verboom M, Gerhards J, Ius F, et al.
Mol Ther
. 2025 Jan;
33(3):1031-1047.
PMID: 39799394
Antibody-mediated rejection (AMR) remains a major complication after solid organ transplantation (SOT). Current treatment options are inefficient and result in drastic impairment of the general immunity. To selectively eliminate responsible...
2.
Stein S, Hansen G, Ssebyatika G, Stroh L, Ochulor O, Herold E, et al.
J Virol
. 2024 Nov;
98(12):e0122324.
PMID: 39494911
The effectiveness of SARS-CoV-2 therapeutic antibodies targeting the spike (S) receptor-binding domain (RBD) has been hampered by the emergence of variants of concern (VOCs), which have acquired mutations to escape...
3.
Mohn N, Grote-Levi L, Wattjes M, Bonifacius A, Holzwart D, Hopfner F, et al.
JAMA Neurol
. 2024 Oct;
PMID: 39374035
Importance: Progressive multifocal leukoencephalopathy (PML) is a life-threatening viral infection with no approved antiviral treatment. Objective: To determine whether restoring the compromised immune system of patients with PML with directly...
4.
Figueiredo C, Chen-Wacker C, Salman J, Carvalho-Oliveira M, Monthe T, Hoffler K, et al.
Sci Transl Med
. 2024 Jul;
16(756):eadi9548.
PMID: 39018368
Immune rejection remains the major obstacle to long-term survival of allogeneic lung transplants. The expression of major histocompatibility complex molecules and minor histocompatibility antigens triggers allogeneic immune responses that can...
5.
Rother T, Horgby C, Schmalkuche K, Burgmann J, Nocke F, Jagers J, et al.
Front Transplant
. 2024 Jul;
2:1183908.
PMID: 38993849
Normothermic machine perfusion provides a powerful tool to improve donor kidney preservation and a route for the delivery of pharmacological or gene therapeutic interventions prior to transplantation. However, perfusion at...
6.
Santamorena M, Tischer-Zimmermann S, Bonifacius A, Mireisz C, Costa B, Khan F, et al.
HLA
. 2024 Jun;
103(6):e15541.
PMID: 38923358
Complications due to HCMV infection or reactivation remain a challenging clinical problem in immunocompromised patients, mainly due to insufficient or absent T-cell functionality. Knowledge of viral targets is crucial to...
7.
Schmalkuche K, Rother T, Burgmann J, Voss H, Hoffler K, Dogan G, et al.
Front Immunol
. 2024 Jun;
15:1404668.
PMID: 38903492
Heart transplantation is associated with major hurdles, including the limited number of available organs for transplantation, the risk of rejection due to genetic discrepancies, and the burden of immunosuppression. In...
8.
Krueger M, Bonifacius A, Dragon A, Santamorena M, Nashan B, Taubert R, et al.
Transpl Int
. 2024 Apr;
37:12720.
PMID: 38655204
Infectious complications, including widespread human cytomegalovirus (CMV) disease, frequently occur after hematopoietic stem cell and solid organ transplantation due to immunosuppressive treatment causing impairment of T-cell immunity. Therefore, in-depth analysis...
9.
Schmalkuche K, Rother T, Besli S, Schwinzer R, Blasczyk R, Petersen B, et al.
Front Immunol
. 2024 Feb;
15:1279050.
PMID: 38352884
Xenotransplantation offers a promising alternative to circumvent the lack of donated human organs available for transplantation. Different attempts to improve the survival of xenografts led to the generation of transgenic...
10.
Liu Z, Luo Y, Kirimunda S, Verboom M, Onabajo O, Gouveia M, et al.
Commun Biol
. 2024 Jan;
7(1):41.
PMID: 38182727
Burkitt lymphoma (BL) is responsible for many childhood cancers in sub-Saharan Africa, where it is linked to recurrent or chronic infection by Epstein-Barr virus or Plasmodium falciparum. However, whether human...