Raghuram Rao Akkinepally
Overview
Explore the profile of Raghuram Rao Akkinepally including associated specialties, affiliations and a list of published articles.
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14
Citations
56
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Recent Articles
1.
Naliganti C, Valupadas C, Akkinepally R, Eesam S
Indian J Pharmacol
. 2019 Dec;
51(5):323-329.
PMID: 31831921
Objectives: Cardiovascular disease (CVD) is the primary cause of death globally despite the advanced health-care facilities. Extensive disparity exists in pharmacotherapy pattern among CVD patients where rational drug use plays...
2.
Achanta P, Raj S, Horam S, Arockiaraj J, Bobbala R, Akkinepally R, et al.
Drug Dev Res
. 2019 Dec;
81(3):366-373.
PMID: 31800126
Seven piperic acid amides along with their lower homologs (12) were synthesized using HATU-DIPEA coupling reagent. All the synthesized derivatives were evaluated for their antibacterial activities against Staphylococcus aureus, Pseudomonas...
3.
Malothu N, Kulandaivelu U, Jojula M, Gunda S, Akkinepally R
Chem Pharm Bull (Tokyo)
. 2018 Oct;
66(10):923-931.
PMID: 30270239
Two series of 3-substituted-7-methyl-5,6,7,8-tetrahydropyrido[4',3':4,5] thieno[2,3-d]pyrimidin-4(3H)-one (6a-k) and 3-substituted-7,2-dimethyl-5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one (7a-k) derivatives were synthesized and characterized using spectral data i.e., IR, H-, C-NMR, Mass and CHN elemental analyses. The synthesized compounds were...
4.
Deb P, Mailavaram R, Chandrasekaran B, Rao Kaki V, Kaur R, Kachler S, et al.
Chem Biol Drug Des
. 2017 Dec;
91(4):962-969.
PMID: 29194979
A series of new molecules containing a thieno[2,3-d]pyrimidine scaffold was synthesized and characterized by adopting an efficient synthetic scheme. The effect of a free or substituted amino group at 2-position...
5.
Kose M, Schiedel A, Bauer A, Poschenrieder H, Burbiel J, Akkinepally R, et al.
Bioorg Med Chem
. 2016 Sep;
24(21):5127-5133.
PMID: 27595538
Adenosine kinase (AdK) is a key player in controlling intra- and extracellular concentrations of the signaling molecule adenosine. Extensive evidence points to an important role of AdK in several diseases,...
6.
Burbiel J, Ghattas W, Kuppers P, Kose M, Lacher S, Herzner A, et al.
ChemMedChem
. 2016 Aug;
11(20):2272-2286.
PMID: 27531666
2-Amino[1,2,4]triazolo[1,5-c]quinazolines were identified as potent adenosine receptor (AR) antagonists. Synthetic strategies were devised to gain access to a broad range of derivatives including novel polyheterocyclic compounds. Potent and selective A...
7.
Achanta P, Akkinepally R, Bobbala R, Achanta A
Magn Reson Chem
. 2015 Sep;
54(2):158-63.
PMID: 26337711
No abstract available.
8.
Achanta P, Gattu R, Belvotagi A, Akkinepally R, Bobbala R, Achanta A
Fitoterapia
. 2014 Dec;
100:166-73.
PMID: 25481374
Ten malabaricane type triterpenes were isolated from the oleoresin of Ailanthus malabarica, out of which six (1-6) were new. For three of the known compounds (7-9), NMR assignments are being...
9.
Deb P, Sharma A, Piplani P, Akkinepally R
Mol Divers
. 2012 Sep;
16(4):803-23.
PMID: 22996404
The reversible inhibition of acetylcholinesterase (AChE) has become a promising target for the treatment of Alzheimer's disease (AD) which is mainly associated with low in vivo levels of acetylcholine (ACh)....
10.
Bheemanapalli L, Balakumar C, Kaki V, Kaur R, Akkinepally R
Med Chem
. 2012 Sep;
9(7):974-84.
PMID: 22974288
Breast cancer is one of the most high-profile malignant diseases in modern society. Among postmenopausal women affected by the disease, a substantial portion has breast tumors that are estrogen-receptor positive....