Joachim C Burbiel
Overview
Explore the profile of Joachim C Burbiel including associated specialties, affiliations and a list of published articles.
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13
Citations
312
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Recent Articles
1.
Rafehi M, Burbiel J, Attah I, Abdelrahman A, Muller C
Purinergic Signal
. 2016 Oct;
13(1):89-103.
PMID: 27766552
The G protein-coupled, ATP- and UTP-activated P2Y receptor is a potential drug target for a range of different disorders, including tumor metastasis, inflammation, atherosclerosis, kidney disorders, and osteoporosis, but pharmacological...
2.
Kose M, Schiedel A, Bauer A, Poschenrieder H, Burbiel J, Akkinepally R, et al.
Bioorg Med Chem
. 2016 Sep;
24(21):5127-5133.
PMID: 27595538
Adenosine kinase (AdK) is a key player in controlling intra- and extracellular concentrations of the signaling molecule adenosine. Extensive evidence points to an important role of AdK in several diseases,...
3.
Burbiel J, Ghattas W, Kuppers P, Kose M, Lacher S, Herzner A, et al.
ChemMedChem
. 2016 Aug;
11(20):2272-2286.
PMID: 27531666
2-Amino[1,2,4]triazolo[1,5-c]quinazolines were identified as potent adenosine receptor (AR) antagonists. Synthetic strategies were devised to gain access to a broad range of derivatives including novel polyheterocyclic compounds. Potent and selective A...
4.
Burbiel J
Mil Med Res
. 2015 Oct;
2:24.
PMID: 26504586
Because posttraumatic stress disorder (PTSD) is a highly debilitating condition, prevention is an important research topic. This article reviews possible prevention approaches that involve the administration of drugs before the...
5.
Wang S, Iring A, Strilic B, Albarran Juarez J, Kaur H, Troidl K, et al.
J Clin Invest
. 2015 Jul;
125(8):3077-86.
PMID: 26168216
Elevated blood pressure is a key risk factor for developing cardiovascular diseases. Blood pressure is largely determined by vasodilatory mediators, such as nitric oxide (NO), that are released from the...
6.
Onnheim K, Christenson K, Gabl M, Burbiel J, Muller C, Oprea T, et al.
Exp Cell Res
. 2014 Feb;
323(1):209-217.
PMID: 24491917
Neutrophils express several G-protein coupled receptors (GPCRs) and they cross regulate each other. We described a novel cross-talk mechanism in neutrophils, by which signals generated by the receptor for ATP...
7.
Cosentino S, Banfi C, Burbiel J, Luo H, Tremoli E, Abbracchio M
J Cell Mol Med
. 2011 Jul;
16(5):1074-84.
PMID: 21762374
Blood levels of extracellular nucleotides (e.g. ATP) are greatly increased during heart ischaemia, but, despite the presence of their specific receptors on cardiomyocytes (both P2X and P2Y subtypes), their effects...
8.
Pekala E, Burbiel J, Muller C
Chirality
. 2008 Nov;
21(8):713-8.
PMID: 18973221
Lactobacillus kefiri DSM 20587 cells were immobilized in calcium alginate and carrageenan. The immobilized cells were used as biocatalysts for the enantioselective reduction of the methyl ketone group of denbufylline...
9.
Burbiel J, Hockemeyer J, Muller C
Beilstein J Org Chem
. 2006 Oct;
2:20.
PMID: 17067400
Background: Poly-substituted xanthine derivatives are an important class of compounds in medicinal chemistry. Substitution at the 8-position of the purine ring is generally accessible by ring closure of a carboxamido-substituted...
10.
Akkari R, Burbiel J, Hockemeyer J, Muller C
Curr Top Med Chem
. 2006 Aug;
6(13):1375-99.
PMID: 16918456
Adenosine receptors belong to the family of G protein-coupled receptors. Four distinct subtypes are known, termed A(1), A(2A), A(2B) and A(3). Adenosine is an important signaling molecule which is released...