Raghavendra S Navath
Overview
Explore the profile of Raghavendra S Navath including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
503
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Recent Articles
1.
Kannan S, Dai H, Navath R, Balakrishnan B, Jyoti A, Janisse J, et al.
Sci Transl Med
. 2012 Apr;
4(130):130ra46.
PMID: 22517883
Cerebral palsy (CP) is a chronic childhood disorder with no effective cure. Neuroinflammation, caused by activated microglia and astrocytes, plays a key role in the pathogenesis of CP and disorders...
2.
Navath R, Menjoge A, Dai H, Romero R, Kannan S, Kannan R
Mol Pharm
. 2011 May;
8(4):1209-23.
PMID: 21615144
Local intravaginal drug therapy is preferred for treatment of ascending genital infections during pregnancy. In the present study, an in situ forming biodegradable hydrogel for sustained release of amoxicillin in...
3.
Menjoge A, Rinderknecht A, Navath R, Faridnia M, Kim C, Romero R, et al.
J Control Release
. 2010 Dec;
150(3):326-38.
PMID: 21129423
Dendrimers offer significant potential as nanocarriers for targeted delivery of drugs and imaging agents. The objectives of this study were to evaluate the transplacental transport, kinetics and biodistribution of PAMAM...
4.
Dai H, Navath R, Balakrishnan B, Guru B, Mishra M, Romero R, et al.
Nanomedicine (Lond)
. 2010 Dec;
5(9):1317-29.
PMID: 21128716
Aim: Understanding the interactions between nanomaterials and disease processes is crucial for designing effective therapeutic approaches. This article explores the unusual neuroinflammation targeting of dendrimers (with no targeting ligands) in...
5.
Wang B, Navath R, Menjoge A, Balakrishnan B, Bellair R, Dai H, et al.
Int J Pharm
. 2010 Jun;
395(1-2):298-308.
PMID: 20580797
Dendrimers have emerged as topical microbicides to treat vaginal infections. This study explores the in vitro, in vivo antimicrobial activity of PAMAM dendrimers, and the associated mechanism. Interestingly, topical cervical...
6.
Navath R, Menjoge A, Wang B, Romero R, Kannan S, Kannan R
Biomacromolecules
. 2010 Apr;
11(6):1544-63.
PMID: 20415504
Dendrimers have emerged as multifunctional carriers for targeted drug delivery, gene delivery and imaging. Improving the functional versatility at the surface for carrying multiple conjugation reactions is becoming vital. Typically,...
7.
Menjoge A, Navath R, Asad A, Kannan S, Kim C, Romero R, et al.
Biomaterials
. 2010 Mar;
31(18):5007-21.
PMID: 20346497
Dendrimers are emerging as promising topical antimicrobial agents, and as targeted nanoscale drug delivery vehicles. Topical intravaginal antimicrobial agents are prescribed to treat the ascending genital infections in pregnant women....
8.
Navath R, Wang B, Kannan S, Romero R, Kannan R
J Control Release
. 2009 Nov;
142(3):447-56.
PMID: 19896998
N-Acetyl cysteine (NAC) is a vital drug currently under clinical trials for the treatment of neuroinflammation in maternal-fetal applications. The free sulfhydryl groups in NAC lead to high plasma protein...
9.
Wang B, Navath R, Romero R, Kannan S, Kannan R
Int J Pharm
. 2009 May;
377(1-2):159-68.
PMID: 19463931
Dendrimers are emerging as potential intracellular drug delivery vehicles. Understanding and improving the cellular efficacy of dendrimer-drug conjugates, can lead to significant in vivo benefits. This study explores efficacy of...
10.
Kurtoglu Y, Navath R, Wang B, Kannan S, Romero R, Kannan R
Biomaterials
. 2009 Jan;
30(11):2112-21.
PMID: 19171376
Understanding and improving drug release kinetics from dendrimer-drug conjugates are key steps to improve their in vivo efficacy. N-Acetyl cysteine (NAC) is an anti-inflammatory agent with significant potential for clinical...