Raffaella Santoro
Overview
Explore the profile of Raffaella Santoro including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
2182
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Recent Articles
1.
Lerra L, Panatta M, Bar D, Zanini I, Tan J, Pisano A, et al.
Mol Cell
. 2024 Apr;
84(9):1667-1683.e10.
PMID: 38599210
The nucleus is composed of functionally distinct membraneless compartments that undergo phase separation (PS). However, whether different subnuclear compartments are connected remains elusive. We identified a type of nuclear body...
2.
Rupasinghe M, Bersaglieri C, Leslie Pedrioli D, Pedrioli P, Panatta M, Hottiger M, et al.
EMBO Rep
. 2024 Feb;
25(3):1453-1468.
PMID: 38332149
Pluripotency is established in E4.5 preimplantation epiblast. Embryonic stem cells (ESCs) represent the immortalization of pluripotency, however, their gene expression signature only partially resembles that of developmental ground-state. Induced PRAMEL7...
3.
Bersaglieri C, Santoro R
Curr Opin Cell Biol
. 2023 May;
81:102171.
PMID: 37230037
The nucleolus is the largest subcompartment of the nucleus, known to be the place of ribosome biogenesis. Emerging evidence has started to implicate the nucleolus in the organization of chromosomes...
4.
Roganowicz M, Bar D, Bersaglieri C, Aprigliano R, Santoro R
Life Sci Alliance
. 2023 May;
6(7).
PMID: 37184661
BAZ2A represses rRNA genes (rDNA) that are transcribed by RNA polymerase I. In prostate cancer (PCa), BAZ2A function goes beyond this role because it represses genes frequently silenced in metastatic...
5.
Randall R, Jourdain C, Nowicka A, Kaduchova K, Kubova M, Ayoub M, et al.
Nucleus
. 2022 Nov;
13(1):277-299.
PMID: 36447428
Nucleus, chromatin, and chromosome organization studies heavily rely on fluorescence microscopy imaging to elucidate the distribution and abundance of structural and regulatory components. Three-dimensional (3D) image stacks are a source...
6.
Muller M, Schaefer M, Fah T, Spies D, Hermes V, Ngondo R, et al.
Stem Cell Reports
. 2022 Apr;
17(5):1070-1080.
PMID: 35452597
The Argonaute proteins (AGOs) are well known for their role in post-transcriptional gene silencing in the microRNA (miRNA) pathway. Here we show that in mouse embryonic stem cells, AGO1&2 serve...
7.
Bersaglieri C, Kresoja-Rakic J, Gupta S, Bar D, Kuzyakiv R, Panatta M, et al.
Nat Commun
. 2022 Mar;
13(1):1483.
PMID: 35304483
Eukaryotic chromosomes are folded into hierarchical domains, forming functional compartments. Nuclear periphery and nucleolus are two nuclear landmarks contributing to repressive chromosome architecture. However, while the role of nuclear lamina...
8.
Santoro R
Cell
. 2021 Dec;
184(25):6019-6021.
PMID: 34890550
The cell's nucleus contains membraneless compartments that create locally high concentrations of factors, thereby facilitating the execution of a variety of nuclear reactions. Two studies report how RNA molecules can...
9.
Diener J, Baggiolini A, Pernebrink M, Dalcher D, Lerra L, Cheng P, et al.
Nat Commun
. 2021 Aug;
12(1):5056.
PMID: 34417458
Melanoma cells rely on developmental programs during tumor initiation and progression. Here we show that the embryonic stem cell (ESC) factor Sall4 is re-expressed in the Tyr::Nras; Cdkn2a melanoma model...
10.
Pena-Hernandez R, Aprigliano R, Carina Frommel S, Pietrzak K, Steiger S, Roganowicz M, et al.
EMBO Rep
. 2021 Aug;
22(11):e53014.
PMID: 34403195
Prostate cancer (PCa) is one of the most prevalent cancers in men. Cancer stem cells are thought to be associated with PCa relapse. Here, we show that BAZ2A is required...