Rafael Ramis
Overview
Explore the profile of Rafael Ramis including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
99
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Recent Articles
1.
Baltasar-Marchueta M, Llona L, M-Alicante S, Barbolla I, Ibarluzea M, Ramis R, et al.
Biomed Pharmacother
. 2024 Apr;
174:116602.
PMID: 38636396
The development of new molecules for the treatment of calmodulin related cardiovascular or neurodegenerative diseases is an interesting goal. In this work, we introduce a novel strategy with four main...
2.
Saez-Matia A, Ibarluzea M, M-Alicante S, Muguruza-Montero A, Nunez E, Ramis R, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38474157
Despite the increasing availability of genomic data and enhanced data analysis procedures, predicting the severity of associated diseases remains elusive in the absence of clinical descriptors. To address this challenge,...
3.
Uceda A, Ramis R, Pauwels K, Adrover M, Marino L, Frau J, et al.
J Inorg Biochem
. 2023 Aug;
247:112344.
PMID: 37542850
α-Synuclein (αS) is a presynaptic protein whose aggregates are considered as a hallmark of Parkinson's disease (PD). Although its physiological function is still under debate, it is widely accepted that...
4.
Ramis R, Ballesteros O, Muguruza-Montero A, M-Alicante S, Nunez E, Villarroel A, et al.
J Biol Chem
. 2023 Jan;
299(2):102850.
PMID: 36587765
The family of small-conductance Ca-activated potassium ion channels (SK channels) is composed of four members (SK1, SK2, SK3, and SK4) involved in neuron-firing regulation. The gating of these channels depends...
5.
Muguruza-Montero A, Ramis R, Nunez E, Ballesteros O, Ibarluzea M, Araujo A, et al.
Protein Sci
. 2021 Aug;
30(10):2029-2041.
PMID: 34392571
Most calmodulin (CaM) targets are α-helices. It is not clear if CaM induces the adoption of an α-helix configuration to its targets or if those targets are selected as they...
6.
Marino L, Ramis R, Casasnovas R, Ortega-Castro J, Vilanova B, Frau J, et al.
Chem Sci
. 2021 Jun;
11(12):3332-3344.
PMID: 34122841
α-Synuclein (αS) aggregation is a hallmark in several neurodegenerative diseases. Among them, Parkinson's disease is highlighted, characterized by the intraneuronal deposition of Lewy bodies (LBs) which causes the loss of...
7.
Ramis R, Ortega-Castro J, Vilanova B, Adrover M, Frau J
Int J Biol Macromol
. 2020 Dec;
169:251-263.
PMID: 33345970
α-Synuclein is an intrinsically disordered protein whose aggregation is related to Parkinson's disease and other neurodegenerative disorders. Metal cations are one of the main factors affecting the propensity of α-synuclein...
8.
Ramis R, Ortega-Castro J, Vilanova B, Adrover M, Frau J
Biomacromolecules
. 2020 Nov;
21(12):5200-5212.
PMID: 33140640
Intraneuronal aggregation of the intrinsically disordered protein α-synuclein is at the core of Parkinson's disease and related neurodegenerative disorders. Several reports show that the concentration of salts in the medium...
9.
Garcia-Diez G, Ramis R, Mora-Diez N
ACS Omega
. 2020 Jun;
5(24):14502-14512.
PMID: 32596588
A systematic study of the thermodynamic stability of various Cu(II) complexes with aminoguanidine (AG) is performed, together with the study of its secondary antioxidant activity. Calculations have been carried out...
10.
Ramis R, Ortega-Castro J, Caballero C, Casasnovas R, Cerrillo A, Vilanova B, et al.
Antioxidants (Basel)
. 2019 Sep;
8(9).
PMID: 31480509
Pyridoxamine, one of the natural forms of vitamin B, is known to be an effective inhibitor of the formation of advanced glycation end products (AGEs), which are closely related to...