Bartolome Vilanova
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Explore the profile of Bartolome Vilanova including associated specialties, affiliations and a list of published articles.
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28
Citations
179
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Recent Articles
1.
Uceda A, Ramis R, Pauwels K, Adrover M, Marino L, Frau J, et al.
J Inorg Biochem
. 2023 Aug;
247:112344.
PMID: 37542850
α-Synuclein (αS) is a presynaptic protein whose aggregates are considered as a hallmark of Parkinson's disease (PD). Although its physiological function is still under debate, it is widely accepted that...
2.
Uceda A, Frau J, Vilanova B, Adrover M
Antioxidants (Basel)
. 2023 Jun;
12(6).
PMID: 37372040
Parkinson's disease (PD) is characterized by dopaminergic neuron degeneration and the accumulation of neuronal inclusions known as Lewy bodies, which are formed by aggregated and post-translationally modified α-synuclein (αS). Oxidative...
3.
Uceda A, Frau J, Vilanova B, Adrover M
Int J Biol Macromol
. 2022 Dec;
229:92-104.
PMID: 36584779
Human alpha-synuclein (αS) is an intrinsically disordered protein highly expressed in dopaminergic neurons. Its amyloid aggregates are the major component of Lewy bodies, which are considered a hallmark of Parkinson's...
4.
Uceda A, Frau J, Vilanova B, Adrover M
Cell Mol Life Sci
. 2022 Jun;
79(6):342.
PMID: 35662377
Parkinson's disease (PD) is one of the most prevalent neurodegenerative disorders affecting the worldwide population. One of its hallmarks is the intraneuronal accumulation of insoluble Lewy bodies (LBs), which cause...
5.
Marino L, Ramis R, Casasnovas R, Ortega-Castro J, Vilanova B, Frau J, et al.
Chem Sci
. 2021 Jun;
11(12):3332-3344.
PMID: 34122841
α-Synuclein (αS) aggregation is a hallmark in several neurodegenerative diseases. Among them, Parkinson's disease is highlighted, characterized by the intraneuronal deposition of Lewy bodies (LBs) which causes the loss of...
6.
Uceda A, Donoso J, Frau J, Vilanova B, Adrover M
Antioxidants (Basel)
. 2021 Mar;
10(2).
PMID: 33672495
Frataxin is a mitochondrial protein which deficiency causes Friedreich's ataxia, a cardio-neurodegenerative disease. The lack of frataxin induces the dysregulation of mitochondrial iron homeostasis and oxidative stress, which finally causes...
7.
Ramis R, Ortega-Castro J, Vilanova B, Adrover M, Frau J
Int J Biol Macromol
. 2020 Dec;
169:251-263.
PMID: 33345970
α-Synuclein is an intrinsically disordered protein whose aggregation is related to Parkinson's disease and other neurodegenerative disorders. Metal cations are one of the main factors affecting the propensity of α-synuclein...
8.
Ramis R, Ortega-Castro J, Vilanova B, Adrover M, Frau J
Biomacromolecules
. 2020 Nov;
21(12):5200-5212.
PMID: 33140640
Intraneuronal aggregation of the intrinsically disordered protein α-synuclein is at the core of Parkinson's disease and related neurodegenerative disorders. Several reports show that the concentration of salts in the medium...
9.
Ramis R, Ortega-Castro J, Caballero C, Casasnovas R, Cerrillo A, Vilanova B, et al.
Antioxidants (Basel)
. 2019 Sep;
8(9).
PMID: 31480509
Pyridoxamine, one of the natural forms of vitamin B, is known to be an effective inhibitor of the formation of advanced glycation end products (AGEs), which are closely related to...
10.
Martinez-Orozco H, Marino L, Uceda A, Ortega-Castro J, Vilanova B, Frau J, et al.
ACS Chem Neurosci
. 2019 Apr;
10(6):2919-2930.
PMID: 30973706
Human α-synuclein is a small monomeric protein (140 residues) essential to maintain the function of the dopaminergic neurons and the neuronal redox balance. However, it holds a dark side since...