Raed A Al-Qawasmeh

A new series of 4-nitroimidazole bearing aryl piperazines , tetrazole and 1,3,4-thiadiazole derivatives was synthesized. All derivatives were screened for their anticancer activity against eight diverse human cancer cell lines...

A new series of redox-active tetraryl-substituted pentacenedione derivatives, namely Ar4-PDs, was prepared through Suzuki-Miyaura coupling reactions between a bis(dibromomethane)pentacenedione and various arene boronic acids. Single-crystal X-ray diffraction analysis and density...

Introduction: Schiff bases are compounds with characteristic features of azomethine linkage (-C=N-). Schiff bases are capable of coordinating with metal ions via azomethine nitrogen. Schiff base derivatives and their metal...

4-((4-(1-benzyl-2-methyl-4-nitro-1-imidazole-5-yl)piperazine-1-yl)methyl)-1-substituted-1-1,2,3-triazole motifs are designed and synthesized click chemistry. The reaction of 1-(-benzyl- 2-methyl-4-nitro-1-imidazole- 5-yl)-4-(prop-2-yn-1-yl) piperazine as new scaffold with diverse primary azides to selectively produce 1,4-disubstituted-1,2,3-triazoles ---. Physicochemical methods: when...

A one-pot, metal-free, light-driven [4+2]-cycloaddition reaction is described by accessing a diverse collection of chromeno[4,3-]quinoline and chromeno[4,3-][1,8]naphthyridine scaffolds in a diastereoselective manner. This process delivered stereoisomers, which were challenging to...

A new series of aminoacetylenic nitroimidazole piperazine hybrid compounds were prepared three-component reaction. Mannich-type reaction was utilized to couple the nitroimidazole containing propargylic moiety with secondary amines and formaldehyde in...

A new chemical library based on the hybridization of cholic acid with the heterocyclic moiety 1,3,4-oxadizole was synthesized, and tested for antimicrobial activity against Gram-positive, Gram-negative bacteria, and fungi. Among...

Piperazine-tagged imidazole derivatives (symmetrical di-substituted piperazine) and - were synthesized through the combination of 4-nitroimidazole derivatives with piperazine moiety. The structural characterization was done by different physical and spectral techniques...

Four new complexes derived from adamantly containing hydrazone () ligand with Cu(II) (), Co(II) (), Ni(II) () and Zn(II) (), have been synthesized and characterized using different physicochemical methods. The...

The incidence of obesity-related diseases like diabetes, cardiovascular diseases, and different types of cancers shed light on the importance of dietary control as preventive and treatment measures. However, long-term dietary...