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Radim Kucera

Explore the profile of Radim Kucera including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 228
Followers 0
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Recent Articles
1.
Tuzun E, Pazderova L, Bavol D, Litecka M, Hnyk D, Ruzickova Z, et al.
Inorg Chem . 2024 Oct; 63(43):20600-20616. PMID: 39393080
Organic amines are found to be abundant in natural living systems. They also constitute an inestimable family of building blocks available in drug design. Considering the man-made cluster [(1,2-CBH)-3,3'-Co(III)] ion...
2.
Harcarova P, Lomozova Z, Kallivretaki M, Karlickova J, Kucera R, Mladenka P
Food Chem . 2024 Sep; 462:141014. PMID: 39226645
Benzoic acids, which are commonly found in food, are also produced by human microbiota from other dietary phenolics. The aim was to investigate the interactions of 8 food-related benzoic acids...
3.
Smutny T, Smutna L, Lochman L, Kamaraj R, Kucera R, Pavek P
Biochem Pharmacol . 2024 Aug; 229:116500. PMID: 39179119
Rifampicin is a model ligand of the pregnane X receptor (PXR), the nuclear receptor involved in the regulation of cytochrome P450 3A4 (CYP3A4). Rifampicin forms several degradation products and metabolites...
4.
Portillo R, Abad C, Synova T, Kastner P, Heblik D, Kucera R, et al.
Toxicology . 2024 Apr; 505:153813. PMID: 38663822
The increasing use of cannabis during pregnancy raises concerns about its impact on fetal development. While cannabidiol (CBD) shows therapeutic promise, its effects during pregnancy remain uncertain. We investigated CBD's...
5.
Abad C, Karahoda R, Orbisova A, Kastner P, Heblik D, Kucera R, et al.
Biol Reprod . 2023 Dec; 110(4):722-738. PMID: 38145492
Maternal immune activation during pregnancy is a risk factor for offspring neuropsychiatric disorders. Among the mechanistic pathways by which maternal inflammation can affect fetal brain development and programming, those involving...
6.
Moravcova M, Lomozova Z, Kucera R, Mladenka P
RSC Adv . 2023 Oct; 13(42):29242-29251. PMID: 37809024
Cobalt intoxication can occur after its release from metal-based prostheses, which is generally clinically severe. Therefore, there is a need for the development of a cobalt chelator since there are...
7.
Novak M, Vajrychova M, Koutsilieri S, Sismanoglou D, Kobrlova T, Prchal L, et al.
ACS Chem Biol . 2023 Aug; 18(9):1993-2002. PMID: 37622522
Tacrine was withdrawn from clinical use as a drug against Alzheimer's disease in 2013, mainly due to drug-induced liver injury. The culprit of tacrine-associated hepatotoxicity is believed to be the...
8.
Plachka K, Pilarova V, Horacek O, Gazarkova T, Vlckova H, Kucera R, et al.
J Sep Sci . 2023 Aug; 46(18):e2300431. PMID: 37568246
Within this review, we thoroughly explored supercritical fluid chromatography (SFC) columns used across > 3000 papers published from the first study carried out under SFC conditions in 1962 to the...
9.
Khalikova M, Jires J, Horacek O, Dousa M, Kucera R, Novakova L
Mass Spectrom Rev . 2023 Jul; 43(3):560-609. PMID: 37503656
The role of mass spectrometry (MS) has become more important in most application domains in recent years. Pharmaceutical analysis is specific due to its stringent regulation procedures, the need for...
10.
Bouz G, Slechta P, Jandourek O, Konecna K, Paterova P, Barta P, et al.
ACS Infect Dis . 2023 Jul; 9(8):1674. PMID: 37486740
No abstract available.