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Radim Kucera

Explore the profile of Radim Kucera including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 228
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Recent Articles
11.
Horacek O, Dhaubhadel U, Holub J, Gruner B, Armstrong D, Kucera R
Chirality . 2023 Jul; 35(12):937-951. PMID: 37461229
Derivatives of the nido-7,8-C B H (1-) (dicarbollide ion) and [3,3'-Co-(1,2-C B H ) ](1-) cobalt sandwich (COSAN) ion represent groups of extremely chemically and thermally stable abiotic compounds. They...
12.
Nawrot D, Bouz G, Jandourek O, Konecna K, Paterova P, Barta P, et al.
Eur J Med Chem . 2023 Jul; 258:115617. PMID: 37423128
Tuberculosis is the number one killer of infectious diseases caused by a single microbe, namely Mycobacterium tuberculosis (Mtb). The success rate of curing this infection is decreasing due to emerging...
13.
Bouz G, Slechta P, Jandourek O, Konecna K, Paterova P, Barta P, et al.
ACS Infect Dis . 2022 Dec; 9(1):79-96. PMID: 36577009
Apart from the SARS-CoV-2 virus, tuberculosis remains the leading cause of death from a single infectious agent according to the World Health Organization. As part of our long-term research, we...
14.
Horacek O, Novakova L, Tuzun E, Gruner B, Svec F, Kucera R
Anal Chem . 2022 Dec; 94(50):17551-17558. PMID: 36475613
The continuous expansion of research in the field of stable carboranes and their wide potential in the drug design require carrying out fundamental studies regarding their chiral separations. Although supercritical...
15.
Horacek O, Portillo A, Dhaubhadel U, Sung Y, Readel E, Kucera R, et al.
Talanta . 2022 Oct; 253:123957. PMID: 36215752
N-acyl homoserine lactones (N-HLs) are signaling molecules synthesized by gram-negative bacteria to communicate in a process called quorum sensing. Most reported methods for the analysis of N-HLs, which are chiral...
16.
Moravcova M, Hrubsa M, Lomozova Z, Catapano M, Argento R, Jirkovsky E, et al.
Med Chem . 2022 Oct; 19(5):495-507. PMID: 36201264
Background: Cobalt is an essential trace element, but it can also rarely cause cobalt toxicity due to its release from cobalt-containing medical devices. Currently, there are no approved selective cobalt...
17.
Kostelansky F, Miletin M, Havlinova Z, Szotakova B, Libra A, Kucera R, et al.
Nucleic Acids Res . 2022 Sep; 50(18):10212-10229. PMID: 36156152
The short oligodeoxynucleotide (ODN) probes are suitable for good discrimination of point mutations. However, the probes suffer from low melting temperatures. In this work, the strategy of using acridine-4-carboxamide intercalators...
18.
Lomozova Z, Hrubsa M, Conte P, Papastefanaki E, Moravcova M, Catapano M, et al.
Food Chem . 2022 Jun; 394:133461. PMID: 35728467
Flavonoids are considered beneficial, but they may exhibit pro-oxidative effects likely due to metal reducing properties. For the first time, 24 structurally related flavonoids were compared for copper reduction, and...
19.
Demuth J, Kantor M, Kucera R, Miletin M, Novakova V
Bioconjug Chem . 2022 Apr; 33(5):788-794. PMID: 35476400
Although triple labeling of molecular beacons has been documented to improve quenching efficiencies and studies generally assume similar benefits at long TaqMan probes, a limited number of works have studied...
20.
Horacek O, Marvalova J, Stilcova K, Holub J, Gruner B, Kucera R
J Chromatogr A . 2022 Apr; 1672:463051. PMID: 35468566
The aspect of the different spatial arrangement of anionic cobalt bis(dicarbollides) and dicarba-nido-undecaboranes remains grossly overlooked despite increased scientific interest. Regarding their growing potential, which does not limit only to...