Rachna Shah
Overview
Explore the profile of Rachna Shah including associated specialties, affiliations and a list of published articles.
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16
Citations
1539
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0
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Recent Articles
1.
Alban T, Riaz N, Parthasarathy P, Makarov V, Kendall S, Yoo S, et al.
Nat Med
. 2024 Sep;
30(11):3209-3222.
PMID: 39349627
Neoantigen immunoediting drives immune checkpoint blockade efficacy, yet the molecular features of neoantigens and how neoantigen immunogenicity shapes treatment response remain poorly understood. To address these questions, 80 patients with...
2.
Ma J, Shah R, Bell A, McDermott N, Pei X, Selenica P, et al.
Int J Radiat Oncol Biol Phys
. 2024 Jul;
121(3):768-779.
PMID: 38997095
Purpose: Homologous recombination deficient (HRD) tumors are exquisitely sensitive to platinum-based chemotherapy and when combined with radiation therapy (RT), leads to improved overall survival in multiple cancer types. Whether a...
3.
Kumar K, Kumar N, Kumar A, Mohammed M, Al-Waisy A, Musa Jaber M, et al.
Comput Intell Neurosci
. 2022 Aug;
2022:5882144.
PMID: 35909858
Chronic diseases are the most severe health concern today, and heart disease is one of them. Coronary artery disease (CAD) affects blood flow to the heart, and it is the...
4.
Setton J, Selenica P, Mukherjee S, Shah R, Pecorari I, McMillan B, et al.
NPJ Breast Cancer
. 2021 Oct;
7(1):135.
PMID: 34635660
Pathogenic germline mutations in the RAD51 paralog genes RAD51C and RAD51D, are known to confer susceptibility to ovarian and triple-negative breast cancer. Here, we investigated whether germline loss-of-function variants affecting...
5.
Samstein R, Krishna C, Ma X, Pei X, Lee K, Makarov V, et al.
Nat Cancer
. 2021 Apr;
1(12):1188-1203.
PMID: 33834176
Immune checkpoint blockade (ICB) has improved outcomes for patients with advanced cancer, but the determinants of response remain poorly understood. Here we report differential effects of mutations in the homologous...
6.
Riaz N, Sherman E, Pei X, Schoder H, Grkovski M, Paudyal R, et al.
J Natl Cancer Inst
. 2021 Jan;
113(6):742-751.
PMID: 33429428
Background: Patients with human papillomavirus-related oropharyngeal cancers have excellent outcomes but experience clinically significant toxicities when treated with standard chemoradiotherapy (70 Gy). We hypothesized that functional imaging could identify patients...
7.
Parekh V, Niccum B, Shah R, Rivera M, Novak M, Geinguenaud F, et al.
Microorganisms
. 2019 Dec;
8(1).
PMID: 31877879
Certain G-rich DNA repeats can form quadruplex in bacterial chromatin that can present blocks to DNA replication and, if not properly resolved, may lead to mutations. To understand the participation...
8.
Damerla R, Lee N, You D, Soni R, Shah R, Reyngold M, et al.
JCO Precis Oncol
. 2019 Sep;
3.
PMID: 31485558
Purpose: A circulating tumor DNA (ctDNA) test to detect plasma Epstein-Barr viral DNA can be used to screen for early nasopharyngeal cancers; however, the reported sensitivity of viral ctDNA tests...
9.
Wang Y, Yang J, Wild A, Wu W, Shah R, Danussi C, et al.
Nat Commun
. 2019 Feb;
10(1):943.
PMID: 30808951
Mutational inactivation of ATRX (α-thalassemia mental retardation X-linked) represents a defining molecular alteration in large subsets of malignant glioma. Yet the pathogenic consequences of ATRX deficiency remain unclear, as do...
10.
Kartush A, Schumacher J, Shah R, Patadia M
Am J Rhinol Allergy
. 2018 Dec;
33(2):203-211.
PMID: 30587005
Background: Chronic rhinosinusitis with nasal polyposis is a complex inflammatory disorder, which is often recalcitrant to medical and surgical management. Recently, biologic agents have been studied as an adjunct treatment...