Rachael Y M Ryan
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Explore the profile of Rachael Y M Ryan including associated specialties, affiliations and a list of published articles.
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10
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60
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Recent Articles
1.
Effect of experimental hookworm infection on insulin resistance in people at risk of type 2 diabetes
Pierce D, McDonald M, Merone L, Becker L, Thompson F, Lewis C, et al.
Nat Commun
. 2023 Jul;
14(1):4503.
PMID: 37495576
The reduced prevalence of insulin resistance and type 2 diabetes in countries with endemic parasitic worm infections suggests a protective role for worms against metabolic disorders, however clinical evidence has...
2.
Cobos C, Bansal P, Wilson D, Jones L, Zhao G, Field M, et al.
Front Med (Lausanne)
. 2022 Oct;
9:934852.
PMID: 36186812
A decline in the prevalence of parasites such as hookworms appears to be correlated with the rise in non-communicable inflammatory conditions in people from high- and middle-income countries. This correlation...
3.
Ryan S, Ruscher R, Johnston W, Pickering D, Kennedy M, Smith B, et al.
Proc Natl Acad Sci U S A
. 2022 Aug;
119(36):e2202795119.
PMID: 36037362
Parasitic helminth infections, while a major cause of neglected tropical disease burden, negatively correlate with the incidence of immune-mediated inflammatory diseases such as inflammatory bowel diseases (IBD). To evade expulsion,...
4.
Ritmejeryte E, Ryan R, Byatt B, Peck Y, Yeshi K, Daly N, et al.
Chem Biol Interact
. 2022 Aug;
368:110124.
PMID: 36007634
Two new galloyl glucosides, galloyl-lawsoniaside A (4) and uromyrtoside (6), were isolated from the polar fraction of Uromyrtus metrosideros leaf extract along with another four previously identified phytochemicals (1, 2,...
5.
Smallwood T, Navarro S, Cristofori-Armstrong B, Watkins T, Tungatt K, Ryan R, et al.
J Biol Chem
. 2021 May;
297(1):100834.
PMID: 34051231
The prevalence of autoimmune diseases is on the rise globally. Currently, autoimmunity presents in over 100 different forms and affects around 9% of the world's population. Current treatments available for...
6.
Ryan R, Seymour J, Loukas A, Lopez J, Ikonomopoulou M, Miles J
Front Immunol
. 2021 May;
12:661082.
PMID: 34040609
Venoms are complex mixtures of toxic compounds delivered by bite or sting. In humans, the consequences of envenomation range from self-limiting to lethal. Critical host defence against envenomation comprises innate...
7.
Ryan R, Fernandez A, Wong Y, Miles J, Cock I
Sci Rep
. 2021 Mar;
11(1):5519.
PMID: 33750911
Bark from the Handroanthus impetiginosus (Mart. ex DC.) Mattos (Bignoniaceae) tree has long been used in traditional South American healing practises to treat inflammation. However, its anti-inflammatory activity has not...
8.
Ryan R, Lutzky V, Herzig V, Smallwood T, Potriquet J, Wong Y, et al.
Toxins (Basel)
. 2020 Oct;
12(11).
PMID: 33114591
Venoms act with remarkable specificity upon a broad diversity of physiological targets. Venoms are composed of proteins, peptides, and small molecules, providing the foundation for the development of novel therapeutics....
9.
Wangchuk P, Shepherd C, Constantinoiu C, Ryan R, Kouremenos K, Becker L, et al.
Infect Immun
. 2019 Jan;
87(4).
PMID: 30670556
Iatrogenic hookworm therapy shows promise for treating disorders that result from a dysregulated immune system, including inflammatory bowel disease (IBD). Using a murine model of trinitrobenzenesulfonic acid-induced colitis and human...
10.
Hayward T, Zhu G, Warrington N, Wong Y, Ryan R, Murray A, et al.
J Allergy Clin Immunol
. 2018 Dec;
143(4):1640-1643.
PMID: 30578878
No abstract available.