R U Janicke
Overview
Explore the profile of R U Janicke including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
26
Citations
3071
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Neise D, Sohn D, Stefanski A, Goto H, Inagaki M, Wesselborg S, et al.
Cell Death Dis
. 2013 Oct;
4:e859.
PMID: 24136223
The p90 ribosomal S6 kinase (RSK) family is a group of highly conserved Ser/Thr kinases that promote cell proliferation, growth, motility and survival. As they are almost exclusively activated downstream...
2.
Sohn D, Budach W, Janicke R
Cell Death Differ
. 2011 Apr;
18(10):1664-74.
PMID: 21475302
Although caspase-2 represents the most conserved caspase across species and was the second caspase identified, its precise function remains enigmatic. In several cell types we show that knockdown of caspase-2...
3.
Schmidt S, Schneider L, Essmann F, Cirstea I, Kuck F, Kletke A, et al.
Oncogene
. 2010 Aug;
29(46):6184-92.
PMID: 20729911
Microtubule-interfering cancer drugs such as paclitaxel (PTX) often cause chemoresistance and severe side effects, including neurotoxicity. To explore potentially novel antineoplastic molecular targets, we investigated the cellular response of breast...
4.
Synthesis of hyaluronan in oesophageal cancer cells is uncoupled from the prostaglandin-cAMP pathway
Twarock S, Rock K, Sarbia M, Weber A, Janicke R, Fischer J
Br J Pharmacol
. 2009 Apr;
157(2):234-43.
PMID: 19338584
Background And Purpose: Cyclooxygenase-2 (COX2) and hyaluronic acid (HA) are common in tumours and both independently promote tumour progression. Furthermore, COX2-dependent synthesis of prostaglandins (PGs) stimulates HA synthase-1 (HAS1) and...
5.
Sohn D, Graupner V, Neise D, Essmann F, Schulze-Osthoff K, Janicke R
Cell Death Differ
. 2009 Feb;
16(6):869-78.
PMID: 19229248
Pifithrin-alpha (PFT-alpha) was shown to specifically block transcriptional activity of the tumor suppressor p53 and was therefore proposed to be useful in preventing the severe side effects often associated with...
6.
Janicke R, Sohn D, Schulze-Osthoff K
Cell Death Differ
. 2008 Mar;
15(6):959-76.
PMID: 18356920
Depending on multiple factors DNA damage leads either to cell cycle arrest or apoptosis. One of the main players deciding the fate of a cell is the tumor suppressor p53...
7.
Neise D, Graupner V, Gillissen B, Daniel P, Schulze-Osthoff K, Janicke R, et al.
Oncogene
. 2007 Aug;
27(10):1387-96.
PMID: 17724463
Among the members of the Bcl-2 family, the multidomain proteins Bax and Bak are crucial for the activation of mitochondria. However, it is still unclear whether they act in a...
8.
Essmann F, Bantel H, Totzke G, Engels I, Sinha B, Schulze-Osthoff K, et al.
Cell Death Differ
. 2003 Aug;
10(11):1260-72.
PMID: 12894214
Recent data suggest that alpha-toxin, the major hemolysin of Staphylococcus aureus, induces cell death via the classical apoptotic pathway. Here we demonstrate, however, that although zVAD-fmk or overexpression of Bcl-2...
9.
Fischer U, Janicke R, Schulze-Osthoff K
Cell Death Differ
. 2003 Mar;
10(1):76-100.
PMID: 12655297
Apoptotic cell death is executed by the caspase-mediated cleavage of various vital proteins. Elucidating the consequences of this endoproteolytic cleavage is crucial for our understanding of cell death and other...
10.
Bantel H, Sinha B, Domschke W, Peters G, Schulze-Osthoff K, Janicke R
J Cell Biol
. 2001 Nov;
155(4):637-48.
PMID: 11696559
Infections with Staphylococcus aureus, a common inducer of septic and toxic shock, often result in tissue damage and death of various cell types. Although S. aureus was suggested to induce...