R M Lawn
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Explore the profile of R M Lawn including associated specialties, affiliations and a list of published articles.
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107
Citations
5050
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Recent Articles
1.
Liu A, Lawn R
Trends Cardiovasc Med
. 2011 Jan;
4(1):40-4.
PMID: 21244908
Lipoprotein(a) is a major inherited risk factor for atherosclerosis. Many of its activities depend on its plasminlike component, apolipoprotein(a). In vitro studies suggest that apolipoprotein(a) could enhance lipid deposition through...
2.
Mikita T, Porter G, Lawn R, Shiffman D
J Biol Chem
. 2001 Sep;
276(49):45729-39.
PMID: 11577090
Macrophage-derived foam cells in atherosclerotic lesions are generally thought to play a major role in the pathology of the disease. Because macrophages play a central role in the inflammatory response,...
3.
Oram J, Lawn R
J Lipid Res
. 2001 Aug;
42(8):1173-9.
PMID: 11483617
It is widely believed that HDL functions to transport cholesterol from peripheral cells to the liver by reverse cholesterol transport, a pathway that may protect against atherosclerosis by clearing excess...
4.
Lou X, Schena M, Horrigan F, Lawn R, Davis R
Methods Mol Biol
. 2001 Jul;
175:323-40.
PMID: 11462845
No abstract available.
5.
Huby T, Dachet C, Lawn R, WICKINGS J, Chapman M, Thillet J
J Biol Chem
. 2001 Apr;
276(25):22209-14.
PMID: 11301336
Lp(a) concentrations vary considerably among individuals and are primarily determined by the apo(a) gene locus. We have previously shown that mean plasma Lp(a) levels in the chimpanzee are significantly higher...
6.
Lawn R, Wade D, Couse T, Wilcox J
Arterioscler Thromb Vasc Biol
. 2001 Mar;
21(3):378-85.
PMID: 11231917
The present study examines the expression of ATP-binding cassette transporter 1 (ABC1) mRNA in normal and atherosclerotic tissues by using in situ hybridization in an effort to better understand the...
7.
Rubanyi G, Freay A, Lawn R
Endothelium
. 2001 Feb;
7(4):253-64.
PMID: 11201523
Elevated plasma level of lipoprotein(a) (Lp(a)) is a well established risk factor for premature atherosclerosis and coronary artery disease. Recent studies showed impaired endothelium-dependent vasodilatation in humans with elevated plasma...
8.
Svindland A, Berg K, Eliassen K, Lawn R, Djurovic S, Alestrom P, et al.
Atherosclerosis
. 2001 Feb;
153(2):349-54.
PMID: 11164423
The aortic root from 21 LPA transgenic mice and 18 control litter mates on cholesterol enriched chow were studied histologically for the presence of atherosclerotic lesions. Serial sections were cut...
9.
Mendez A, Lin G, Wade D, Lawn R, Oram J
J Biol Chem
. 2000 Nov;
276(5):3158-66.
PMID: 11073951
Efflux of excess cellular cholesterol mediated by lipid-poor apolipoproteins occurs by an active mechanism distinct from passive diffusion and is controlled by the ATP-binding cassette transporter ABCA1. Here we examined...
10.
Tai J, Brooks E, Liang S, Somogyi R, Rosete J, Lawn R, et al.
Arterioscler Thromb Vasc Biol
. 2000 Oct;
20(10):2184-91.
PMID: 11031202
Vascular injury induces extensive alteration to the extracellular matrix (ECM). These changes contribute to lesion formation and promote cell migration and proliferation. To elucidate ECM response to arterial injury, we...