R K Tuominen
Overview
Explore the profile of R K Tuominen including associated specialties, affiliations and a list of published articles.
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Articles
55
Citations
220
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Recent Articles
1.
Sarajarvi T, Jantti M, Paldanius K, Natunen T, Wu J, Makinen P, et al.
Neuropharmacology
. 2018 Aug;
141:76-88.
PMID: 30138694
Abnormal protein kinase C (PKC) function contributes to many pathophysiological processes relevant for Alzheimer's disease (AD), such as amyloid precursor protein (APP) processing. Phorbol esters and other PKC activators have...
2.
El-Kawy O, Garcia-Horsman J, Tuominen R
Appl Radiat Isot
. 2016 Oct;
118:258-265.
PMID: 27693738
Tc-tricarbonyl-vardenafil was specifically radiosynthesized for diagnostic evaluation of erectile dysfunction with a radiochemical yield ~97.2%. It was stable in saline up to 15h and in serum for more than 6h....
3.
Mus L, Dravolina O, Bespalov A, Kaenmaki M, Talka R, Salminen O, et al.
Zh Nevrol Psikhiatr Im S S Korsakova
. 2012 Sep;
112(7):48-52.
PMID: 23011431
Catechol-O-methyltransferase (COMT) remains an important regulatory element in prefrontal cortex dopamine homeostasis. The literature data suggest that individual differences in COMT activity (Val158Met polymorphism) might have indirect downstream effects on...
4.
Planken A, Porokuokka L, Hanninen A, Tuominen R, Andressoo J
J Neurosci Methods
. 2010 Oct;
194(1):122-31.
PMID: 20951734
In Parkinson's disease (PD) midbrain dopaminergic (DA) neurons degenerate and die, causing loss of motor function. Currently no therapies exist to ameliorate neurodegeneration or to restore DA neurons, although neurotrophic...
5.
Lozeva V, Tuominen R, Mannisto P, Tuomisto L
Inflamm Res
. 2002 May;
51 Suppl 1:S44-5.
PMID: 12013404
No abstract available.
6.
Vainio P, Tuominen R
Nicotine Tob Res
. 2001 Jun;
3(2):177-82.
PMID: 11403732
Cotinine is the major metabolite of nicotine. It has nicotine-like biological activity, but its potency is low. We studied cotinine binding to nicotinic receptors labelled with [3H]epibatidine. In membranes from...
7.
Tornquist K, Vainio P, Bjorklund S, Titievsky A, Dugue B, Tuominen R
Biochem J
. 2000 Sep;
351(Pt 1):47-56.
PMID: 10998346
Redox modulation participates in the regulation of intracellular free calcium concentration ([Ca(2+)](i)) in several cell types. In thyroid cells, including FRTL-5 cells, changes in [Ca(2+)](i) regulate several important functions, including...
8.
Vainio P, Tornquist K, Tuominen R
Toxicol Appl Pharmacol
. 2000 Mar;
163(2):183-7.
PMID: 10698676
Cotinine is the major metabolite of nicotine. It has some biological activity, but its pathophysiological effects are largely unclear. We studied whether cotinine initiates calcium transients or affects those induced...
9.
Ahtee L, Tuominen R
Trends Pharmacol Sci
. 1999 Nov;
20(10):391-3.
PMID: 10577250
No abstract available.
10.
Lozeva V, Anttila E, Tuominen R, Hippelainen M, Mannisto P, Tuomisto L
Inflamm Res
. 1999 Apr;
48(2):81-5.
PMID: 10202993
Objective And Design: Histamine can modulate feeding behaviour and hormone release; therefore we examined the hypothalamic histamine system, the growth pattern and the serum levels of prolactin and growth hormone...